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Variations in red blood cell polyamines in brain tumour patients treated with stereotactic radiosurgery
C von Essen1, P Elworthy, E Hitchcock
1Department of Neurosurgery, University of Birmingham, Warley, West Midlands, UK.
Neurological Research
|June 1, 1989
Abstract:
Red blood cell polyamine levels were followed in 13 patients treated with stereotactic radiosurgery for various types of brain tumours. In the most malignant tumours radiosurgery resulted in a decrease in spermine and an increase in spermidine levels. This discrepancy between variations in polyamine levels was not found after conventional radiotherapy. The results may indicate a change in tumour polyamine activity induced by high energy radiotherapy.