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Screening Foodstuffs for Class 1 Integrons and Gene Cassettes
Published on: June 19, 2015
Preferential carriage of class 2 integrons in Acinetobacter baumannii CC113 and novel singletons
M S Ramírez1, S Montaña1, M Cassini2
1Instituto de Microbiología y Parasitología Médica (IMPaM, UBA-CONICET),Facultad de Medicina,Universidad de Buenos Aires,Argentina.
Abstract:
Our understanding of the distribution of integrons associated with multidrug resistance in Acinetobacter baumannii isolates around the world remains incomplete. The association between the class 1 and 2 integron A. baumannii-positive isolates (n = 60), recovered since 1982 from 11 Argentinean hospitals, and the circulating lineages, was investigated. While class 2 integrons were highly significantly associated with clonal lineage CC113B/CC79P (P = 0·009) and novel singletons (P = 0·001), class 1 integrons were found not to be associated with CC109B/CC1P or other lineages. The study reveals a differential distribution of class 2 integrons in lineages, and suggests that the prevalence of intI2 in Argentina is related to the emergence of novel singletons in recent years and to the abundance of CC113B/CC79P, which has been the local dominant lineage for several decades.
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