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Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
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Aortic arch calcification is strongly associated with coronary artery calcification
Adem Adar1, Hakan Erkan2, Tayyar Gokdeniz2
1Karabuk University Hospital, Department of Cardiology, Turkey.
VASA. Zeitschrift Fur Gefasskrankheiten
|February 21, 2015
Summary
Aortic arch calcification (AAC) on chest X-rays strongly predicts coronary artery calcification (CAC) risk. This non-invasive method effectively identifies patients with low and high CAC scores.
Area of Science:
- Cardiovascular Imaging
- Radiology
- Preventive Cardiology
Background:
- Coronary artery calcification (CAC) is a marker of atherosclerosis.
- Evaluating CAC typically requires advanced imaging like MDCT.
- A simpler method to predict CAC risk is needed.
Purpose of the Study:
- To investigate the association between aortic arch calcification (AAC) and CAC.
- To determine if standard chest radiography can predict CAC risk based on AAC.
Main Methods:
- Prospective enrollment of 248 patients undergoing MDCT for CAC scoring.
- Standard posterior-anterior chest radiography images were used to grade AAC on a four-point scale.
- Statistical analysis including correlation, logistic regression, and ROC curve analysis was performed.
Main Results:
- AAC grades and age were significantly correlated with CAC score (r=0.676 and r=0.518, respectively).
- Presence of AAC was independently associated with CAC (OR: 11.20).
- An AAC grade of ≥2 strongly predicted high-risk CAC score (OR: 27.42) with high accuracy (95%).
Conclusions:
- Aortic arch calcification (AAC) is a significant and independent predictor of coronary artery calcification (CAC).
- AAC evaluation on standard chest radiography demonstrates high discriminative performance for identifying patients at low and high CAC risk.
- Chest radiography offers a valuable, accessible tool for preliminary CAC risk assessment.
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