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Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

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As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

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Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
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Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

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During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
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Analgesia and Pain Management01:25

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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
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Related Experiment Video

Updated: Apr 17, 2026

Objective Nociceptive Assessment in Ventilated ICU Patients: A Feasibility Study Using Pupillometry and the Nociceptive Flexion Reflex
06:04

Objective Nociceptive Assessment in Ventilated ICU Patients: A Feasibility Study Using Pupillometry and the Nociceptive Flexion Reflex

Published on: July 4, 2018

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Pain management in the elderly.

Monica Malec1, Joseph W Shega2

  • 1Section of Geriatrics and Palliative Medicine, University of Chicago, 5841 S.Maryland avenue, Chicago, IL 60537, USA.

The Medical Clinics of North America
|February 22, 2015
PubMed
Summary

Persistent pain is common in older adults, impacting their well-being. Effective management involves thorough assessment and tailored analgesic treatment, often guided by the World Health Organization

Keywords:
Older adultPainPain assessmentPain management

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Last Updated: Apr 17, 2026

Objective Nociceptive Assessment in Ventilated ICU Patients: A Feasibility Study Using Pupillometry and the Nociceptive Flexion Reflex
06:04

Objective Nociceptive Assessment in Ventilated ICU Patients: A Feasibility Study Using Pupillometry and the Nociceptive Flexion Reflex

Published on: July 4, 2018

9.4K

Area of Science:

  • Geriatric Medicine
  • Pain Management
  • Pharmacology

Background:

  • Persistent pain significantly affects older adults, leading to considerable morbidity.
  • Comprehensive assessment is crucial for effective pain management in this demographic.

Purpose of the Study:

  • To review pain assessment and management strategies for older adults.
  • To focus on commonly used analgesics for non-cancer pain in the elderly.

Main Methods:

  • Review of pain assessment components: presence, intensity, characteristics, interference, conditions, behaviors, morbidity, treatments, and coping.
  • Discussion of analgesic selection using the World Health Organization's 3-step pain ladder.
  • Emphasis on shared decision-making in balancing analgesic benefits and burdens.

Main Results:

  • Optimal pain management requires a detailed assessment of various pain-related factors.
  • Analgesics should be chosen to reduce pain and improve patient well-being.
  • The World Health Organization's 3-step ladder provides a framework for analgesic selection in non-cancer pain.

Conclusions:

  • Systematic pain assessment is the foundation for effective management in older adults.
  • Shared decision-making is vital for optimizing analgesic therapy.
  • This review highlights key considerations for managing persistent pain in the elderly.