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Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Mesenteric panniculitis: still an ambiguous condition
N Badet1, N Sailley1, C Briquez2
1Service de radiologie viscérale, CHRU Besançon, hôpital Jean-Minjoz, 3, boulevard Fleming, 25030 Besançon, France.
Purpose:
To study the possible relationship between mesenteric panniculitis (MP) visible on computed tomography (CT) and the presence of an underlying neoplastic disease.
Patients And Methods:
A retrospective analysis of 158 patients with CT examinations that revealed the presence of MP was performed. CT images were analyzed by two different radiologists using morphological criteria validated in the radiological literature. The presence, frequency and type of neoplastic lesions associated with MP were assessed.
Results:
MP was asymptomatic in 96/158 patients (61%). Fat halo sign and pseudocapsule were visible on CT in 89/158 (56%) and 93/158 (59%) patients, respectively. Underlying neoplastic disease was present in 88/158 patients (56%). The neoplastic diseases most often associated with MP were lymphoma (28%), melanoma (18%), colorectal cancer (15%) and prostate cancer (13%).
Conclusion:
MP has typical CT appearance and is associated with underlying neoplastic disease in 56% of patients. Such levels of association might suggest that MP may be considered as a paraneoplastic condition. Hence, incidental depiction of MP on CT in a patient without known neoplastic disease should incite radiologists to further scrutinize CT examination for presence of synchronous neoplastic lesions.
Insights
Mesenteric panniculitis (MP), a condition visible on CT scans, is linked to underlying cancer in over half of patients. Radiologists should carefully examine CTs for cancer when MP is incidentally found.
Area of Science:
- Radiology
- Oncology
- Pathology
Background:
- Mesenteric panniculitis (MP) is a rare condition affecting the mesentery.
- Its association with neoplastic diseases requires further investigation.
Purpose of the Study:
- To investigate the relationship between mesenteric panniculitis (MP) detected via computed tomography (CT) and the presence of underlying neoplastic disease.
Main Methods:
- Retrospective analysis of 158 patients with MP on CT scans.
- Radiological assessment of CT images for MP characteristics.
- Evaluation for associated neoplastic lesions.
Main Results:
- MP was asymptomatic in 61% of patients.
- Neoplastic disease was present in 56% of patients with MP.
- Commonly associated cancers included lymphoma, melanoma, colorectal, and prostate cancer.
Conclusions:
- Mesenteric panniculitis has a characteristic CT appearance.
- MP is associated with underlying neoplastic disease in 56% of cases, suggesting a potential paraneoplastic etiology.
- Incidental MP findings on CT warrant thorough examination for synchronous neoplastic lesions.
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