Mesenteric panniculitis: still an ambiguous condition

N Badet1, N Sailley1, C Briquez2

  • 1Service de radiologie viscérale, CHRU Besançon, hôpital Jean-Minjoz, 3, boulevard Fleming, 25030 Besançon, France.

Abstract

Insights

Mesenteric panniculitis (MP), a condition visible on CT scans, is linked to underlying cancer in over half of patients. Radiologists should carefully examine CTs for cancer when MP is incidentally found.

Area of Science:

  • Radiology
  • Oncology
  • Pathology

Background:

  • Mesenteric panniculitis (MP) is a rare condition affecting the mesentery.
  • Its association with neoplastic diseases requires further investigation.

Purpose of the Study:

  • To investigate the relationship between mesenteric panniculitis (MP) detected via computed tomography (CT) and the presence of underlying neoplastic disease.

Main Methods:

  • Retrospective analysis of 158 patients with MP on CT scans.
  • Radiological assessment of CT images for MP characteristics.
  • Evaluation for associated neoplastic lesions.

Main Results:

  • MP was asymptomatic in 61% of patients.
  • Neoplastic disease was present in 56% of patients with MP.
  • Commonly associated cancers included lymphoma, melanoma, colorectal, and prostate cancer.

Conclusions:

  • Mesenteric panniculitis has a characteristic CT appearance.
  • MP is associated with underlying neoplastic disease in 56% of cases, suggesting a potential paraneoplastic etiology.
  • Incidental MP findings on CT warrant thorough examination for synchronous neoplastic lesions.

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