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Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

849
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
849
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

869
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
869
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

468
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
468
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

348
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
348
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

607
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
607
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

482
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
482

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Related Experiment Video

Updated: Apr 17, 2026

Isolation and Characterization of Cardiac Mesenchymal Stromal Cells from Endomyocardial Bioptic Samples of Arrhythmogenic Cardiomyopathy Patients
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Candidial Endocarditis: A Single-Institute Pathological Analysis.

Pradeep Vaideeswar1

  • 1Department of Pathology (Cardiovascular and Thoracic Division), Seth GS Medical College, Parel, Mumbai, 400012, India, shreeprajai@yahoo.co.in.

Mycopathologia
|February 23, 2015
PubMed
Summary

Candidial endocarditis, a fungal infection of the heart lining, is often linked to healthcare. This study highlights its right-sided, valvular nature and associated risk factors like central venous catheters.

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Area of Science:

  • Cardiology
  • Infectious Diseases
  • Pathology

Background:

  • Infective endocarditis (IE) is increasingly associated with medical interventions.
  • Fungal IE accounts for a significant portion of IE cases, with Candida species being predominant.
  • Candidial endocarditis presents unique challenges in diagnosis and management.

Purpose of the Study:

  • To describe the pathological experience of candidial endocarditis.
  • To identify risk factors and clinical characteristics of candidial endocarditis.
  • To analyze outcomes and complications of candidial endocarditis.

Main Methods:

  • A retrospective analysis of 14 cases of candidial endocarditis.
  • Inclusion of surgically excised cardiac tissues and autopsied cases over a 14-year period.
  • Review of clinical data, risk factors, and autopsy findings.

Main Results:

  • Candidial endocarditis was predominantly right-sided and valvular.
  • Healthcare-associated invasive infections were observed in 12 of 14 cases.
  • Key risk factors included underlying heart disease, central venous catheterization, and prolonged antibiotic therapy.
  • Only five cases were diagnosed antemortem.
  • Mortality in autopsied patients was linked to septicemia and embolic complications.

Conclusions:

  • Candidial endocarditis is a significant complication of healthcare-associated infections.
  • Early diagnosis and prompt management are crucial for improving outcomes.
  • Understanding risk factors is essential for prevention and early detection.