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Testosterone suppression in opioid users: a systematic review and meta-analysis

Monica Bawor1, Herman Bami2, Brittany B Dennis3

  • 1MiNDS Neuroscience Graduate Program, McMaster University, 1280 Main St. W., Hamilton, ON L8S 4L8, Canada; Population Genomics Program, Chanchlani Research Centre, McMaster University, 1280 Main St. W., Hamilton, ON L8S 4L8, Canada.

Drug and Alcohol Dependence
|February 24, 2015
PubMed
Summary

Opioids significantly suppress testosterone levels in men, but not in women. This hormonal imbalance may impact treatment outcomes for opioid dependence and pain management, highlighting different endocrine disruption mechanisms between sexes.

Keywords:
MethadoneOpiatesPrescription opioidsSex hormonesTestosterone

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