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Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
Published on: June 28, 2018
Diagnosing ventilator-associated pneumonia in pediatric intensive care
Elias Iosifidis1, Stella Stabouli2, Anastasia Tsolaki2
1Infectious Diseases Unit, 3rd Department of Pediatrics, Aristotle University School of Medicine, Hippokration Hospital, Thessaloniki, Greece.
Abstract:
The Centers for Disease Control and Prevention's criteria were applied by independent investigators for ventilator-associated pneumonia (VAP) diagnosis in critically ill children and compared with tracheal aspirate cultures (TACs). In addition, correlation between antibiotic use, VAP incidence, and epidemiology of TACs was investigated. A modest agreement (κ = 0.41) was found on radiologic findings between 2 investigators. VAP incidence was 7.7 episodes per 1,000 ventilator days, but positive TACs were the most significant factor for driving high antimicrobial usage in the pediatric intensive care unit.
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