Five new diarylheptanoids from the rhizomes of Curcuma kwangsiensis and their antiproliferative activity
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Shao-Dan Chen1, Jin-Tao Gao2, Jing-Gong Liu2
1The Second Clinical College, Guangzhou University of Chinese Medicine, Guangzhou 510000, China; Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510000, China; Postdoctoral Programme, Guangzhou University of Chinese Medicine, Guangzhou 510000, China.
Abstract:
Five new diarylheptanoids (1-5), along with nine known ones (6-14), were isolated from the rhizomes of Curcuma kwangsiensis. Their structures were established on the basis of spectroscopic analyses. Compounds 1-3 were cyclic diarylheptanoids rarely discovered from C. kwangsiensis. Of all the isolated compounds, compound 4 showed moderate antiproliferative activity on HH and HaCaT cells.
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