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Updated: Apr 17, 2026

Refined Murine Model of Idiopathic Pulmonary Fibrosis
Published on: June 17, 2025
Fibrous pleural plaques detected at autopsy
Nursel Türkmen1, Bülent Eren2, Ümit Naci Gündoğmuş3
1Department of Forensic Medicine, Uludağ University Medical Faculty, Department of Bursa Morgue, Council of Forensic Medicine of Turkey, Bursa, Turkey.
Abstract:
The reported case was a 84-year-old male, dead after a traffic accident. The death was considered to be suspicious by prosecutor and an autopsy was mandated. In macroscopic autopsy investigation left tibia, fibula and multiple rib fractures, widespread seborrheic keratoses, and hyperpigmented skin lesions were detected. In the left chest cavity blood content and white colored lesions spread on the left parietal pleura and chest surface of the thoracic diaphragm were observed. The histological examination of the pleural lesions revealed fibrotic hyalinized structures with calcified foci. Investigation of pleural plaques in forensic autopsy is important for scientific classification of this interesting entity.
Insights
Forensic autopsy revealed pleural plaques in an 84-year-old male, initially suspicious after a traffic accident. Histological examination confirmed these fibrotic, calcified lesions on the pleura and diaphragm.
Area of Science:
- Forensic pathology
- Pulmonary pathology
Background:
- Autopsies are crucial for determining cause of death, especially in suspicious cases.
- Pleural plaques are fibrous or fibrocalcific thickenings of the parietal pleura.
Observation:
- A traffic accident victim, an 84-year-old male, presented with fractures and skin lesions.
- Macroscopic examination revealed blood in the left chest cavity and white lesions on the pleura and diaphragm.
- Histological analysis of pleural lesions showed fibrotic, hyalinized structures with calcified foci.
Findings:
- The autopsy identified pleural plaques, characterized by fibrotic and calcified changes.
- These findings were incidental in the context of the fatal traffic accident.
Implications:
- Investigating pleural plaques during forensic autopsies aids in their scientific classification.
- Understanding the nature and prevalence of pleural plaques in autopsy cases is important for public health and occupational disease research.
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