Related Experiment Video
Updated: Apr 17, 2026

Nasal Wipes for Influenza A Virus Detection and Isolation from Swine
Published on: December 4, 2015
Is wet swab superior to dry swab as an intranasal screening test?
Hideharu Hagiya1, Mitsunobu Mio2, Tomoko Murase3
1Department of Clinical Laboratory, Microbiology Division, Tsuyama Central Hospital, Okayama, 708-0841 Japan ; Department of Nursing, Tsuyama Central Hospital, Okayama, 708-0841 Japan.
Abstract:
Methicillin-resistant Staphylococcus aureus is still a great concern, and recognition of the carrier is essential for appropriate infection control in intensive care units. The utility of wet swab compared to dry swab as an intranasal screening test has not been well assessed yet. A comparative study of the wet and dry swab in its ability to detect the organism was performed against critically ill patients, and it was found that there were no statistically significant differences between the two different methods. The wet swab did not show increased sensitivity compared to dry one.
Insights
Intranasal screening for methicillin-resistant Staphylococcus aureus (MRSA) using wet swabs showed no significant difference in detecting the organism compared to dry swabs in critically ill patients. This finding suggests dry swabs are equally effective for MRSA carrier recognition in intensive care units.
Area of Science:
- Infectious Diseases
- Microbiology
- Critical Care Medicine
Background:
- Methicillin-resistant Staphylococcus aureus (MRSA) poses a significant threat in healthcare settings, particularly intensive care units (ICUs).
- Effective infection control relies on accurate identification of MRSA carriers.
- The optimal method for intranasal MRSA screening requires further evaluation.
Purpose of the Study:
- To compare the diagnostic utility of wet versus dry swabs for intranasal MRSA screening.
- To assess if wet swabs offer increased sensitivity in detecting MRSA carriers compared to dry swabs.
Main Methods:
- A comparative study was conducted on critically ill patients in an ICU setting.
- Intranasal samples were collected using both wet and dry swab techniques.
- The detection rates of MRSA for both methods were statistically analyzed.
Main Results:
- No statistically significant difference was observed in the ability of wet and dry swabs to detect MRSA.
- The sensitivity of the wet swab method was not found to be superior to the dry swab method.
- Both methods demonstrated comparable performance in identifying MRSA carriers.
Conclusions:
- Wet swabs do not offer an advantage over dry swabs for intranasal MRSA screening in critically ill patients.
- Dry swabs are a viable and effective option for MRSA carrier detection in ICUs.
- Current screening protocols may not require a change in swab type for MRSA detection.

