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Shunt Surgery, Right Heart Catheterization, and Vascular Morphometry in a Rat Model for Flow-induced Pulmonary Arterial Hypertension
Published on: February 11, 2017
Potts shunt in patients with primary pulmonary hypertension
Sue Hyun Kim1, Woo-Sung Jang1, Hong-Gook Lim1
1Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine.
Insights
Idiopathic pulmonary arterial hypertension (PAH) in children has high mortality. A Potts shunt procedure offered good short-term results for a 12-year-old girl with severe PAH and right ventricular failure.
Area of Science:
- Pediatric Cardiology
- Cardiovascular Surgery
- Pulmonary Hypertension
Background:
- Idiopathic pulmonary arterial hypertension (PAH) leads to right-sided heart failure and death, with high pediatric mortality.
- Current pharmacological therapies have limited efficacy in improving outcomes for children with PAH.
- Novel treatment strategies are crucial for managing pediatric PAH and improving survival.
Observation:
- A 12-year-old girl presented with suprasystemic idiopathic pulmonary hypertension and significant right ventricular failure.
- The patient underwent a Potts shunt procedure, creating an anastomosis between the left pulmonary artery and the descending aorta.
- This palliative surgical technique aimed to alleviate the pressure on the right ventricle.
Findings:
- The Potts shunt procedure resulted in good short-term outcomes for the patient.
- The surgical intervention provided immediate palliation for the severe symptoms of pediatric PAH.
- This case demonstrates the potential benefit of the Potts shunt in managing complex pediatric cardiovascular conditions.
Implications:
- The Potts shunt may serve as a viable palliative option for select pediatric patients with refractory idiopathic pulmonary arterial hypertension.
- Further research is warranted to evaluate the long-term efficacy and safety of the Potts shunt in this population.
- This case highlights the importance of considering surgical interventions for severe pediatric cardiovascular diseases when medical management is insufficient.
Abstract:
Idiopathic pulmonary arterial hypertension eventually leads to right-sided heart failure and sudden death. Its mortality rate in children is still high, despite improvements in pharmacological therapy, and therefore novel treatments are necessary. The Potts shunt, which creates an anastomosis between the left pulmonary artery and the descending aorta, has been proposed as a theoretically promising palliative surgical technique to decompress the right ventricle. We report the case of a 12-year-old girl with suprasystemic idiopathic pulmonary hypertension and right ventricular failure who underwent a Potts shunt for palliation with good short-term results.
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