Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

The Oral Microbiota

The Oral Microbiota

The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...

Biofilms

Biofilms

Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...

Antimicrobial Effectiveness

Antimicrobial Effectiveness

The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Structural Basis of Pore Formation in the Mannose Phosphotransferase System by Pediocin PA-1.

Applied and environmental microbiology·2021

Same author

Lipid Nanoparticle-mRNA Formulations for Therapeutic Applications.

Accounts of chemical research·2021

Same author

Enhancing of broadband sound absorption through soft matter.

Materials horizons·2021

Same author

Metabolomic Analysis Reveals the Therapeutic Effects of MBT1805, a Novel Pan-Peroxisome Proliferator-Activated Receptor Agonist, on α-Naphthylisothiocyanate-Induced Cholestasis in Mice.

Frontiers in pharmacology·2021

Same author

High Temperature Deformation Behavior and Microstructure Evolution of Low-Density Steel Fe30Mn11Al1C Micro-Alloyed with Nb and V.

Materials (Basel, Switzerland)·2021

Same author

An oversampling method for multi-class imbalanced data based on composite weights.

PloS one·2021

Search research articles

Related Experiment Video

Updated: Apr 17, 2026

Author Spotlight: Metallic Nanocomposites to Eliminate Antibiotic-Resistant Bacteria

Author Spotlight: Metallic Nanocomposites to Eliminate Antibiotic-Resistant Bacteria

Published on: October 4, 2024

Killing dental pathogens using antibacterial graphene oxide.

Jianliang He¹, Xiaodan Zhu, Zhengnan Qi

¹Department of Endodontics, Ninth People's Hospital, School of Medicine, Shanghai Key Laboratory of Stomatology, and §Shanghai Research Institute of Stomatology, Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University , 639 ZhiZaoJu Road, Shanghai 200011, People's Republic of China.

ACS Applied Materials & Interfaces

|February 24, 2015

Summary

Graphene oxide (GO) effectively inhibits growth of dental pathogens like Streptococcus mutans. GO damages bacterial cell walls, showing promise for novel dental care and therapies.

Keywords:

Fusobacterium nucleatum Porphyromonas gingivalis Streptococcus mutans antibacterial material dental pathogens graphene oxide

More Related Videos

Therapeutic Effectiveness of a Dietary Supplement for Management of Halitosis in Dogs

Therapeutic Effectiveness of a Dietary Supplement for Management of Halitosis in Dogs

Published on: July 6, 2015

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

Published on: March 31, 2021

Related Experiment Videos

Last Updated: Apr 17, 2026

Author Spotlight: Metallic Nanocomposites to Eliminate Antibiotic-Resistant Bacteria

Author Spotlight: Metallic Nanocomposites to Eliminate Antibiotic-Resistant Bacteria

Published on: October 4, 2024

Therapeutic Effectiveness of a Dietary Supplement for Management of Halitosis in Dogs

Therapeutic Effectiveness of a Dietary Supplement for Management of Halitosis in Dogs

Published on: July 6, 2015

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

Published on: March 31, 2021

Area of Science:

Nanomaterials Science
Microbiology
Dental Research

Background:

Dental caries and periodontal diseases are linked to oral microbes.
Graphene oxide (GO) is a graphene derivative with known antimicrobial properties.

Purpose of the Study:

To investigate the antimicrobial efficacy of graphene oxide (GO) against key dental pathogens.
To explore the potential of GO in dental care applications.

Main Methods:

Utilized MTT assay, colony forming units (CFU) counting, growth curve analysis, live/dead staining, and confocal laser scanning microscopy (CLSM).
Employed Transmission Electron Microscopy (TEM) to visualize bacterial cell damage.

Main Results:

GO nanosheets demonstrated significant inhibition of dental pathogen growth.
TEM revealed GO disrupts bacterial cell wall and membrane integrity, leading to leakage of intracellular contents.

Conclusions:

Graphene oxide (GO) exhibits potent antibacterial activity against dental pathogens.
GO shows promising potential for future applications in dental care and therapeutic strategies.