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Updated: Jul 13, 2026

Evaluation of Mammary Gland Development and Function in Mouse Models
Published on: July 21, 2011
Hormonal modulation of the rat mammary gland gamma-glutamyltranspeptidase
M Ríos1, J Puente, M Sapag-Hagar
1Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago.
Abstract:
1. The in vivo effect of estradiol and domperidone (a hypophysis stimulator of prolactin secretion) in immature ovariectomized-adrenalectomized and hypophysectomized rat mammary gland was studied. 2. gamma-Glutamyltranspeptidase activity was used to evaluate the role of estradiol in the specific response of the gland to prolactin. 3. Our results suggest that the activity of gamma-glutamyltranspeptidase, like casein and lactose synthetase, is part of the specific response of the gland to prolactin.
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