Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microbiota of the Respiratory Tract01:29

Microbiota of the Respiratory Tract

44
The human respiratory tract, comprising the upper and lower segments, serves as a critical interface with the external environment. The upper respiratory tract (URT)—including the nostrils, sinuses, pharynx, and oropharynx—is heavily colonized by microbes, while the lower respiratory tract (LRT), composed of the larynx, trachea, bronchi, and lungs, was long thought to be sterile. However, recent molecular studies have revealed that the lungs are not devoid of microbes but act more...
44
Bacterial Phylum Chlamydiae01:29

Bacterial Phylum Chlamydiae

803
The phylum Chlamydiae or Chlamydiota is composed of a single order, Chlamydiales. This phylum consists entirely of obligate intracellular parasites that infect eukaryotic hosts. While human pathogens within this group have been studied extensively, the phylum encompasses many species capable of interacting with various eukaryotic organisms. Members of Chlamydiae are typically small cocci, approximately 0.5 μm in diameter, and exhibit a distinctive developmental cycle. As is characteristic...
803
Atypical Pneumonia01:14

Atypical Pneumonia

67
Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease...
67
Common Respiratory Disorders01:31

Common Respiratory Disorders

1.9K
Respiratory disorders, a prevalent health concern globally, are generally divided into two primary categories: upper and lower respiratory tract disorders. The categorization is based on the area of the respiratory system they affect.
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
1.9K
Acute Respiratory Failure-III01:30

Acute Respiratory Failure-III

1.2K
Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
1.2K
Bacterial Phylum Actinobacteria01:30

Bacterial Phylum Actinobacteria

890
Coryneform bacteria are gram-positive, aerobic, nonmotile rods that exhibit irregular, club-shaped, or V-shaped arrangements. Their V-shape results from snapping division, where the inner cell wall layer forms the cross-wall, while the outer layer remains intact until it ruptures on one side, causing the daughter cells to bend away.The primary genera are Corynebacterium and Arthrobacter. Corynebacterium includes diverse species, ranging from saprophytes to pathogens like Corynebacterium...
890

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of Bronchiectasis on Healthcare Resource Utilization and Direct Medical Costs of Managing Comorbid Chronic Obstructive Pulmonary Disease, Asthma, and Rheumatoid Arthritis in the United States.

The clinical respiratory journal·2025
Same author

Zinc Promotes Mitochondrial Health Through PGC-1alpha Enhancing Bacterial Clearance in Macrophages Infected with <i>Mycobacterium avium Complex</i>.

International journal of molecular sciences·2025
Same author

Study Design and Rationale for The Breathe Easier With Tadalafil Therapy for Exercise-Related Dyspnea in COPD-PH (BETTER COPD-PH).

Pulmonary circulation·2025
Same author

Molecular Approaches to Treating Chronic Obstructive Pulmonary Disease: Current Perspectives and Future Directions.

International journal of molecular sciences·2025
Same author

Evaluating elexacaftor/tezacaftor/ivacaftor (ETI; Trikafta™) for treatment of patients with non-cystic fibrosis bronchiectasis (NCFBE): A clinical study protocol.

PloS one·2025
Same author

PGC-1α activation to enhance macrophage immune function in mycobacterial infections.

PloS one·2025

Related Experiment Video

Updated: Apr 17, 2026

Assessing Respiratory Immune Responses to Haemophilus Influenzae
06:32

Assessing Respiratory Immune Responses to Haemophilus Influenzae

Published on: June 29, 2021

2.7K

Achromobacter respiratory infections.

Colin E Swenson1, Ruxana T Sadikot

  • 11 Division of Pulmonary, Critical Care, and Sleep Medicine, College of Medicine, University of Florida, Gainesville, Florida; and.

Annals of the American Thoracic Society
|February 24, 2015
PubMed
Summary

Achromobacteria are opportunistic pathogens causing lung infections, often community-acquired pneumonias, particularly in cancer patients. Treatment can be challenging due to multidrug resistance, but extended-spectrum penicillins and cephalosporins show promise.

Keywords:
antimicrobial drug resistancebacterial pneumoniabronchiectasisgram-negative bacteriavirulence factors

More Related Videos

Rapid and Specific Detection of Acinetobacter baumannii Infections Using a Recombinase Polymerase Amplification/Cas12a-based System
07:59

Rapid and Specific Detection of Acinetobacter baumannii Infections Using a Recombinase Polymerase Amplification/Cas12a-based System

Published on: April 25, 2025

1.6K
Author Spotlight: Advancing Rapid Detection of Respiratory Pathogens Using Microfluidic Chip
06:11

Author Spotlight: Advancing Rapid Detection of Respiratory Pathogens Using Microfluidic Chip

Published on: March 29, 2024

2.8K

Related Experiment Videos

Last Updated: Apr 17, 2026

Assessing Respiratory Immune Responses to Haemophilus Influenzae
06:32

Assessing Respiratory Immune Responses to Haemophilus Influenzae

Published on: June 29, 2021

2.7K
Rapid and Specific Detection of Acinetobacter baumannii Infections Using a Recombinase Polymerase Amplification/Cas12a-based System
07:59

Rapid and Specific Detection of Acinetobacter baumannii Infections Using a Recombinase Polymerase Amplification/Cas12a-based System

Published on: April 25, 2025

1.6K
Author Spotlight: Advancing Rapid Detection of Respiratory Pathogens Using Microfluidic Chip
06:11

Author Spotlight: Advancing Rapid Detection of Respiratory Pathogens Using Microfluidic Chip

Published on: March 29, 2024

2.8K

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Pulmonology

Background:

  • Achromobacteria are environmental bacteria with opportunistic pathogenic potential.
  • Infections are increasingly reported, yet clinical significance and treatment remain uncertain for many physicians.
  • Multidrug resistance complicates effective management of Achromobacteria infections.

Purpose of the Study:

  • To review and analyze published cases of non-cystic fibrosis Achromobacteria lung infections.
  • To elucidate the pathogenic potential and antimicrobial susceptibility patterns of Achromobacteria in lung infections.
  • To provide insights for clinicians managing these challenging infections.

Main Methods:

  • Systematic review of all published case reports of non-cystic fibrosis Achromobacteria lung infections.
  • Analysis of clinical presentation, patient demographics, and outcomes.
  • Evaluation of antimicrobial susceptibility data.

Main Results:

  • The majority of reviewed cases were community-acquired pneumonias (88%).
  • Hematologic and solid organ malignancies were the most frequent comorbidities.
  • Infections were challenging to treat but showed good response to extended-spectrum penicillins and cephalosporins (e.g., ticarcillin, piperacillin, cefoperazone).

Conclusions:

  • Achromobacteria are significant causes of community-acquired pneumonia, especially in immunocompromised patients.
  • Effective treatment strategies are crucial due to emerging drug resistance.
  • Extended-spectrum penicillins and cephalosporins represent viable therapeutic options for Achromobacteria lung infections.