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Effects of bestatin on intrauterine growth of rat fetuses
M Furuhashi1, S Mizutani, O Kurauchi
1Department of Obstetrics and Gynecology, Nagoya University School of Medicine, Japan.
Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme
|July 1, 1989
Abstract:
Pregnant Wistar rats were injected with bestatin, a specific inhibitor of aminopeptidase M. Placental aminopeptidase M activity was inhibited by injection of bestatin, and fetal body weight was statistically lower than that in the saline-injected or control group. Our present data suggest that placental aminopeptidase M plays an important role in fetal growth.