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Relationship of Haemophilus influenzae type b pilus structure and adherence to human erythrocytes
J R Gilsdorf1, W J Judd, M Cinat
1Department of Pediatrics and Communicable Diseases, C. S. Mott Children's Hospital, Ann Arbor, Michigan 48109-0244.
Six strains of Haemophilus influenzae type b, some expressing immunologically different pili, showed identical patterns of binding to erythrocytes that were characterized for 38 blood group antigens. All six strains appeared to bind to the Anton antigen, as they agglutinated all erythrocytes tested except cord erythrocytes and those characterized as Lu(a-b-), dominant type, including Anton-negative cells.
Six strains of Haemophilus influenzae type b, some expressing immunologically different pili, showed identical patterns of binding to erythrocytes that were characterized for 38 blood group antigens. All six strains appeared to bind to the Anton antigen, as they agglutinated all erythrocytes tested except cord erythrocytes and those characterized as Lu(a-b-), dominant type, including Anton-negative cells.