Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stages of General Anesthesia01:22

Stages of General Anesthesia

2.5K
Various sedation levels offer significant advantages in facilitating procedural interventions for patients undergoing medical or invasive surgical procedures. These levels span from anxiolysis to general anesthesia, providing a spectrum of sedative effects to cater to specific patient needs. Anxiolysis reduces anxiety and is achieved through minimal sedation, enabling patients to remain awake and responsive while feeling more at ease during the procedure. This level can benefit minor...
2.5K
Parenteral Anesthetics: Overview01:24

Parenteral Anesthetics: Overview

968
Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
968
General Anesthesia: Overview01:24

General Anesthesia: Overview

1.1K
Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
1.1K
Sedatives and Hypnotics: Overview01:23

Sedatives and Hypnotics: Overview

2.2K
Sedatives are drugs that alleviate anxiety, while hypnotics induce sleep. Both classes of medication suppress neuronal activity, leading to a calming effect for sedatives and facilitating sleep for hypnotics.
Sedative-hypnotics are categorized into barbiturates, benzodiazepines (BZDs), and non-benzodiazepines or Z-drugs. These drugs work by suppressing central nervous system activity, and this suppression is dose-dependent. Older sedative medications, like barbiturates, follow a linear curve in...
2.2K
Skeletal Muscle Relaxants: Therapeutic Uses01:31

Skeletal Muscle Relaxants: Therapeutic Uses

1.2K
Skeletal muscle relaxants are used to relax muscle tone and alleviate painful muscle contractions. However, the choice of skeletal muscle relaxants depends on the duration of the surgical procedure in order to minimize potential side effects. Skeletal muscle relaxants like neuromuscular blocking agents [NMBAs] are commonly employed as adjuvants alongside general anesthetics in clinical settings. NMBAs are also used to maintain controlled ventilation during surgery of the larynx or pharynx...
1.2K
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

1.1K
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reduce Burnout, Improve Safety and Efficiency: Consider Prosocial Behavior.

AORN journal·2026
Same author

Addressing Social Determinants of Health.

AORN journal·2025
Same author

Adapting the World Health Organization's Surgical Safety Checklist to High-Income Settings: A Hybrid Effectiveness-Implementation Trial Protocol.

Annals of surgery open : perspectives of surgical history, education, and clinical approaches·2024
Same author

Safe Staffing, Competency Assessment, and Onboarding.

AORN journal·2024
Same author

Does the Type of Surgical Headwear Worn in the OR Matter? A Review of Evidence and Opinions.

AORN journal·2023
Same author

Prevention of Perioperative Pressure Injury.

AORN journal·2023
Same journal

Guideline Quick View: Environmental Hygiene.

AORN journal·2026
Same journal

Air Quality as a Cornerstone of Sterile Technique.

AORN journal·2026
Same journal

Brief Limb-Focused Prewarming in Adults Undergoing General Anesthesia: A Randomized Trial.

AORN journal·2026
Same journal

Clinical Issues - July 2026.

AORN journal·2026
Same journal

The Power of Learning From Mishaps and Missteps.

AORN journal·2026
Same journal

Embracing the Future of Care.

AORN journal·2026
See all related articles

Related Experiment Video

Updated: Apr 17, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

20.9K

Back to basics: procedural sedation.

Lisa Spruce

    AORN Journal
    |February 25, 2015
    PubMed
    Summary
    This summary is machine-generated.

    Perioperative registered nurses (RNs) can safely administer procedural sedation with proper training and facility protocols. This enhances patient comfort by reducing pain and anxiety during surgical procedures.

    Keywords:
    analgesiaanesthesiamoderate sedationprocedural sedation

    More Related Videos

    Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
    05:39

    Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia

    Published on: May 26, 2023

    2.7K
    Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
    09:36

    Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device

    Published on: September 24, 2020

    3.3K

    Related Experiment Videos

    Last Updated: Apr 17, 2026

    Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
    07:54

    Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

    Published on: December 6, 2016

    20.9K
    Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
    05:39

    Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia

    Published on: May 26, 2023

    2.7K
    Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
    09:36

    Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device

    Published on: September 24, 2020

    3.3K

    Area of Science:

    • Nursing
    • Anesthesiology
    • Perioperative Care

    Background:

    • Registered nurses (RNs) frequently administer procedural sedation in the perioperative setting.
    • Procedural sedation is crucial for managing patient pain and anxiety during surgery.

    Purpose of the Study:

    • To outline the essential components of facility sedation protocols.
    • To emphasize the role of RNs in administering procedural sedation.
    • To ensure safe and effective sedation practices in perioperative settings.

    Main Methods:

    • Development of facility sedation protocols guided by state laws, CMS guidelines, and accreditation requirements.
    • Defining RN training requirements, roles, and credentialing processes.
    • Establishing guidelines for medication use and consultation with anesthesia personnel.

    Main Results:

    • Appropriately trained perioperative RNs can safely and effectively administer procedural sedation.
    • Comprehensive protocols support RNs in their sedation administration role.
    • Clear guidelines improve patient outcomes by managing pain and anxiety.

    Conclusions:

    • Perioperative RNs are capable of providing safe and effective procedural sedation.
    • Robust training, physician guidance, and clear protocols are vital for successful implementation.
    • Standardized protocols enhance patient care and safety in the perioperative environment.