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Updated: Apr 17, 2026

Porphyromonas gingivalis as a Model Organism for Assessing Interaction of Anaerobic Bacteria with Host Cells
Published on: December 17, 2015
Differences in immune response to Porphyromonas gingivalis
Laura M Tebloeva1, Zalina E Revazova2, Kate G Fabrikant3
1Postdoctoral, Department of Periodontology, Moscow State University of Medicine and Dentistry, Moscow, Russia,
Abstract:
About 341 (average age of 38.0 ± 2.5 years) patients with periodontal disease were included in this study. All the patients were not treated for periodontal disease for a period of 6 months prior to this study. All the patients were not on any hormonal therapy. Antibodies to Porphyromonas gingivalis (P. gingivalis) were determined in blood serum by enzyme-linked immunosorbent assay (ELISA) method. Findings from this study suggest immune response to P. gingivalis is more effective in males than in females. Smoking and obesity tends to reduce effective immune response.
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