Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cancer Prevention02:59

Cancer Prevention

8.7K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
8.7K
Cancer Prevention02:59

Cancer Prevention

3.1K
3.1K
Cancer Therapies02:49

Cancer Therapies

10.8K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
10.8K
Cancer Therapies02:49

Cancer Therapies

3.0K
3.0K
Cancer02:18

Cancer

56.3K
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
56.3K
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

6.4K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
6.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Awareness and best practices in using ketogenic therapy to treat serious mental illness: a modified Delphi consensus.

Frontiers in nutrition·2026
Same author

Addressing malnutrition in cancer care: Where do postgraduate oncology students stand?

Clinical nutrition ESPEN·2025
Same author

Nutritional support is beneficial in cancer patients with malnutrition and inflammation.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer·2025
Same author

Potential Benefits from Physical Exercise in Advanced Cancer Patients Undergoing Systemic Therapy? A Narrative Review of the Randomized Clinical Trials.

Current oncology (Toronto, Ont.)·2024
Same author

Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma.

BMC medicine·2024
Same author

Sarcopenia: nothing is as it seems. Author's response to Gonzalez, Cruz-Jentoft, Phillips and Prado.

Current opinion in clinical nutrition and metabolic care·2024

Related Experiment Video

Updated: Apr 17, 2026

Using Mouse Mammary Tumor Cells to Teach Core Biology Concepts: A Simple Lab Module
10:39

Using Mouse Mammary Tumor Cells to Teach Core Biology Concepts: A Simple Lab Module

Published on: June 18, 2015

13.9K

Toward a cancer-specific diet.

Federico Bozzetti1, Beth Zupec-Kania2

  • 1Faculty of Medicine, University of Milan, Italy.

Clinical Nutrition (Edinburgh, Scotland)
|February 25, 2015
PubMed
Summary

Calorie restriction and ketogenic diets show promise for cancer patients by targeting cancer cell metabolism. While human data is limited, these nutritional strategies may offer therapeutic benefits by exploiting cancer cells

Keywords:
Calorie restriction and tumour growthDietary manipulation and tumour growthFat-enriched dietHigh fat/carbohydrate ratioKetogenic dietNutritional support and tumour growth

More Related Videos

Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer
05:30

Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer

Published on: October 31, 2025

432
Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies
09:29

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies

Published on: September 30, 2016

14.6K

Related Experiment Videos

Last Updated: Apr 17, 2026

Using Mouse Mammary Tumor Cells to Teach Core Biology Concepts: A Simple Lab Module
10:39

Using Mouse Mammary Tumor Cells to Teach Core Biology Concepts: A Simple Lab Module

Published on: June 18, 2015

13.9K
Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer
05:30

Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer

Published on: October 31, 2025

432
Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies
09:29

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies

Published on: September 30, 2016

14.6K

Area of Science:

  • Oncology
  • Metabolic Research
  • Nutritional Science

Background:

  • Cancer cells predominantly utilize anaerobic glycolysis for energy.
  • Calorie restriction has been explored to inhibit experimental tumor growth.
  • Ketone bodies, a product of calorie restriction, are toxic to cancer cells with defective mitochondria.

Purpose of the Study:

  • To review data on tumor growth during starvation or nutritional support.
  • To analyze the use of normocaloric ketogenic diets in cancer patients.
  • To evaluate the impact of ketogenic diets on cancer cells versus normal cells.

Main Methods:

  • Review of existing literature on caloric restriction and nutritional support in cancer patients.
  • Analysis of studies on normocaloric ketogenic diets in cancer treatment.
  • Comparison of tumor growth modulation in animal models versus human patients.

Main Results:

  • Modulation of tumor growth by calorie restriction or nutritional support in humans is unlikely due to differences in tumor/host ratios and treatment duration compared to animal models.
  • Paucity of data exists regarding the direct impact of these interventions on human tumor growth.

Conclusions:

  • Maintaining normal body weight and lean body mass through adequate nutrition is crucial for cancer patients.
  • Ketogenic diets, potentially toxic to cancer cells while well-tolerated by patients, represent a promising future nutritional approach.