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The induction of micronuclei in human lymphocytes by in vitro irradiation with alpha particles from plutonium-239
A Bilbao1, J S Prosser, A A Edwards
1Departamento de Biologíe Celular e Histología, Facultad de Medicina, Universidad deĺ País Vasco, Leioa, Vizcaya, Spain.
International Journal of Radiation Biology
|September 1, 1989
Abstract:
Human peripheral blood lymphocytes were irradiated for 24 h in vitro with plutonium-239 citrate. The dose response for micronucleus induction using the cytochalasin B blocking technique fitted well to a linear relationship. Comparison with published data from the same laboratory using X-irradiation, indicated an RBE of 3.6 for alpha particles at low doses.