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Updated: Apr 17, 2026

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population
Published on: January 31, 2025
Correlation between distal radial cortical thickness and bone mineral density
Tracy Webber1, Shaun P Patel1, Michael Pensak1
1Department of Orthopaedic Surgery, University of Connecticut, Farmington, CT; Department of Orthopaedic Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, MA; Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center, Boston, MA.
Distal radius cortical thickness positively correlates with hip bone density, not spine density. Thinner cortices in distal radius fractures may indicate bone insufficiency requiring further evaluation.
Area of Science:
- Orthopedics
- Radiology
- Bone Densitometry
Background:
- Distal radius fractures are common in postmenopausal women.
- Assessing bone health is crucial for fracture management and osteoporosis screening.
Purpose of the Study:
- To evaluate the reliability of measuring distal radius cortical thickness from radiographs.
- To investigate the correlation between distal radius cortical thickness and bone density measurements from dual-energy x-ray absorptiometry (DXA).
Main Methods:
- Orthopedic surgeons measured radial bicortical width on wrist radiographs of 80 women over 50 with distal radius fractures.
- Measurements were correlated with femoral and lumbar spine bone density data from DXA scans.
- Inter-rater reliability was assessed using intra-class correlation coefficients.
Main Results:
- High inter-rater reliability (ICC=0.91) was found for measuring average bicortical thickness.
- A statistically significant positive correlation was observed between distal radius bicortical thickness and femoral bone density.
- No significant association was found between distal radius bicortical thickness and lumbar spine bone density.
Conclusions:
- Distal radius cortical thickness is a reliable radiographic measure and correlates positively with hip bone density.
- This finding suggests potential similarities in bone quality between the appendicular radius and femur.
- Identifying thinned distal radial cortices may prompt further DXA evaluation for bone insufficiency.
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