Related Experiment Video
Updated: Apr 17, 2026

Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides
Published on: May 26, 2019
Advances in tandem reactions with organozinc reagents
Ju Hyun Kim1, Young Ok Ko, Jean Bouffard
1Department of Chemistry and Nano Science (BK 21 Plus), Ewha Womans University, 120-750 Seoul, Korea. bouffard@ewha.ac.kr sanggi@ewha.ac.kr.
Abstract:
The design and implementation of tandem reactions provides organic chemists with numerous challenges, in particular that of undesired cross-reactivity between substrates. Among organometallics, the use of organozinc reagents in tandem reactions provides several advantages as a result of their broad functional group tolerance and compatibility with transition metals. This review highlights prominent examples of recent advances in tandem reactions with organozinc reagents that illustrate their potential in organic synthesis.
More Related Videos
Related Concept Videos
Cycloaddition Reactions: Overview
Diazonium Group Substitution with Halogens and Cyanide: Sandmeyer and Schiemann Reactions
Ziegler–Natta Chain-Growth Polymerization: Overview
Cyclohexenones via Michael Addition and Aldol Condensation: The Robinson Annulation
Nucleophilic Aromatic Substitution of Aryldiazonium Salts: Aromatic SN1
In the Sandmeyer reaction, for example, the diazonio group is replaced by a chloro, bromo,...
Alkenes via Reductive Coupling of Aldehydes or Ketones: McMurry Reaction

