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A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Terpenoids from Ligularia kangtingensis
Jin Tian1, Guang-Bo Xie1, Ya Xie1
1Department of Biotechnology, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, PR China.
Background:
Ligularia kangtingensis, a species from the genus Ligularia (Compositae), is an indigenous plant in Southwest China and more than 20 species in this genus have been used as folk medicines in China.
Objective:
The chemical constituents of the whole plant of L. kangtingensis were studied.
Materials And Methods:
The dried whole plants were extracted with ethanol. Its chemical constituents were mainly isolated and purified by silica gel and Sephadex LH-20 column chromatography and their structures were identified on the basis of spectral analysis.
Results:
Twelve known terpenoids, including two monoterpenoids, five sesquiterpenoids and five triterpenoids, were isolated and identified from the whole plant of L. kangtingensis.
Conclusion:
All of the 12 known compounds were isolated for the first time from L. kangtingensis.