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The developing asymmetry: revisiting a perceptual and diagnostic challenge
Elissa R Price1, Bonnie N Joe, Edward A Sickles
1From the Department of Radiology and Biomedical Imaging, Division of Women's Imaging, University of California-San Francisco, 1600 Divisadero St, Room C-250, San Francisco, CA 94115.
Radiology
|February 25, 2015
Summary
Developing asymmetry, a change in appearance over time, warrants increased suspicion. This review covers its identification, evaluation using mammography and sonography, biopsy, and associated pathologies.
Area of Science:
- Radiology
- Breast Imaging
- Diagnostic Imaging
Background:
- Asymmetry is a common finding in breast imaging.
- Developing asymmetry, characterized by changes over time, requires careful evaluation due to increased suspicion.
- Distinguishing developing asymmetry from stable asymmetry is crucial for patient management.
Purpose of the Study:
- To define the key features of developing asymmetry.
- To review imaging tools for identifying and evaluating developing asymmetry in mammography and sonography.
- To discuss percutaneous biopsy and differential diagnoses for developing asymmetry.
Main Methods:
- Literature review of developing asymmetry in breast imaging.
- Analysis of imaging characteristics distinguishing developing from stable asymmetry.
- Review of biopsy techniques and pathological correlations.
Main Results:
- Developing asymmetry exhibits distinct imaging features indicating change over time.
- Mammography and sonography offer complementary roles in evaluating developing asymmetry.
- Percutaneous biopsy is often necessary for definitive diagnosis.
Conclusions:
- Developing asymmetry is a significant finding requiring a high index of suspicion.
- Appropriate imaging interpretation and biopsy are essential for managing patients with developing asymmetry.
- Understanding benign and malignant causes is critical for accurate diagnosis.
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