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Growth of Indonesian Infants Compared With World Health Organization Growth Standards

Pramita G Dwipoerwantoro1, Muchtaruddin Mansyur, Hanifah Oswari

  • 1*Department of Child Health †Department of Public Health, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia ‡Women's and Children's Health Research Institute, University of Adelaide §Department of Gastroenterology, Hepatology and Nutrition Unit, Royal Children's Hospital, Brisbane, Queensland, Australia.

Insights

World Health Organization (WHO) growth standards may not accurately reflect Indonesian infant growth. This study found Indonesian infants were lighter, shorter, and had smaller head circumferences than WHO references.

Area of Science:

  • Pediatrics
  • Growth Monitoring
  • Global Health

Background:

  • The applicability of World Health Organization (WHO) growth standards for South East Asian infants is debated.
  • Accurate growth assessment is crucial for early detection of developmental issues.

Purpose of the Study:

  • To evaluate the growth of Indonesian infants (breast-fed and formula-fed) against WHO growth standards.
  • To provide contemporary growth data for Indonesian infants.

Main Methods:

  • A prospective cohort study involving 160 healthy Indonesian infants aged 2-6 weeks.
  • Infants were exclusively breast-fed or formula-fed for at least 6 months, with follow-up to 12 months.
  • Growth parameters (weight-for-age, length-for-age, head circumference-for-age, weight-for-length) were compared to WHO Growth Reference Study data.

Main Results:

  • Indonesian infants were lighter, shorter, and had smaller head circumferences compared to the WHO reference population.
  • Z-scores for weight-for-age, length-for-age, and head circumference-for-age declined from birth to 6 weeks, then increased until 3 months.
  • At 6 weeks, significant proportions of infants had z-scores below -2 SD for weight-for-age and length-for-age, particularly formula-fed infants.

Conclusions:

  • The WHO growth standards do not adequately represent the growth patterns of this cohort of Indonesian infants.
  • Current WHO standards may lead to an overestimation of underweight and stunted growth in Indonesian children.
Abstract

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