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Updated: Apr 17, 2026

Transcranial Pulse Stimulation for Alzheimer's Patients
Published on: April 4, 2025
Living with mild to moderate Alzheimer patients increases the caregiver's burden at 6 months
Alessandra Raccichini1, Liana Spazzafumo2, Simona Castellani3
1Neurology Unit, Italian National Research Center on Aging, Ancona, Italy alessandraraccichini@tiscali.it.
Abstract:
The objective of our study was to demonstrate that living with a person affected by mild to moderate Alzheimer's disease can lead to an increased perception of the caregiver's burden using the Caregiver Burden Inventory (CBI). The sample consisted of 153 dyads, caregiver-patient. At baseline, a greater perception of the caregiver's burden was observed in the live-in caregivers. A further increase in the total burden of the live-in caregivers was noticed at the 6-month follow-up. More specifically, with the inclusion of correction factors such as the caregiver's age and the CBI subscales at baseline, the social and emotional burden becomes statistically significant (P < .001). The present paper confirms our hypothesis that live-in caregivers perceive a greater burden than nonlive-in, and this difference increases further after 6 months. The difference in involvement between live-in and nonlive-in caregivers could be the foundation to tailor more specific interventions.
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