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Updated: Apr 17, 2026

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

Migraine affects white-matter tract integrity: A diffusion-tensor imaging study.

Catherine D Chong¹, Todd J Schwedt²

¹Department of Neurology, Mayo Clinic, USA.

Cephalalgia : an International Journal of Headache

|February 26, 2015

Summary

This summary is machine-generated.

White-matter tracts in the brain are altered in migraine patients, with longer migraine duration correlating with increased tract integrity changes. Diffusion tensor imaging revealed specific diffusivity differences in key brain regions.

Keywords:

Migraine diffusion-tensor imaging fibertracts neuroimaging pain white matter

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Last Updated: Apr 17, 2026

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression

Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression

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DTI of the Visual Pathway - White Matter Tracts and Cerebral Lesions

DTI of the Visual Pathway - White Matter Tracts and Cerebral Lesions

Published on: August 26, 2014

Area of Science:

Neuroimaging
Neurology
Brain Anatomy

Background:

White-matter tract alterations in migraine are not fully understood.
Diffusion tensor imaging (DTI) is a key tool for investigating brain structure.
The relationship between migraine duration and white-matter integrity requires further exploration.

Purpose of the Study:

To investigate white-matter tract integrity in migraine patients using DTI.
To examine alterations in tracts associated with the brain's pain network.
To determine if migraine duration influences white-matter structure.

Main Methods:

Utilized global probabilistic tractography to analyze specific white-matter tracts.
Included 23 adults with migraine and 18 healthy controls.
Assessed anterior thalamic radiations, corticospinal tracts, and inferior longitudinal fasciculi.

Main Results:

Migraine patients exhibited increased mean diffusivity (MD) and radial diffusivity (RD) in several white-matter tracts.
No significant differences in fractional anisotropy (FA) were found between groups.
A positive correlation was observed between migraine duration and MD in specific tracts.

Conclusions:

White-matter integrity is demonstrably altered in individuals with migraine.
Increased duration of migraine is associated with more pronounced changes in white-matter tract integrity.
Findings highlight potential neuroanatomical changes underlying migraine pathophysiology.