Related Experiment Video
Updated: Apr 17, 2026
Author Spotlight: Enhancing Coronary Artery Revascularization
Published on: September 15, 2023
Risk factors for mortality of patients undergoing coronary artery bypass graft surgery
Carlos Alberto Dos Santos1, Marcos Aurélio Barboza de Oliveira1, Antônio Carlos Brandi1
1Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brasil.
Insights
Coronary artery bypass grafting (CABG) mortality is linked to dialysis, neurologic dysfunction, and longer bypass times. Advanced age and elevated creatinine also increase risk in CABG patients.
Area of Science:
- Cardiovascular Surgery
- Medical Research
- Patient Outcomes
Background:
- Coronary artery bypass grafting (CABG) is a common procedure with generally low mortality.
- Identifying specific risk factors for mortality in CABG patients is crucial for improving outcomes.
Purpose of the Study:
- To investigate and identify key risk factors associated with mortality in patients undergoing on-pump coronary artery bypass grafting surgery.
Main Methods:
- A retrospective study of 1,628 patients undergoing on-pump CABG between December 1999 and February 2012.
- Statistical analyses included t-tests, Mann-Whitney, Fisher's exact test, and logistic regression with Odds Ratio (OR) and 95% Confidence Intervals (CI).
Main Results:
- Mortality rate was 8.7% (141 out of 1,628 patients).
- Significant risk factors for mortality identified: dialysis (OR=7.61), neurologic dysfunction type I (OR=4.42), intra-aortic balloon pump (IABP) use (OR=3.38), cardiopulmonary bypass time (OR=3.09), elevated serum creatinine (OR=2.67), age > 65 (OR=2.31), and longer hospital admission to surgery time (OR=1.53).
Conclusions:
- Dialysis, neurologic dysfunction, IABP use, prolonged cardiopulmonary bypass time, elevated creatinine, advanced age, and delayed surgery are significant risk factors for mortality in on-pump CABG patients.
Introduction:
Coronary artery bypass grafting is a safe procedure performed worldwide with low rates of mortality and morbidity in general population.
Objective:
To investigate risk factors for mortality of patients undergoing coronary artery bypass grafting coronary artery bypass grafting surgery.
Methods:
A total of 1,628 consecutive patients undergoing on-pump coronary artery bypass grafting were retrospectively studied from December 1999 to February 2012. Data analysis involved paired Student t test, Mann-Whitney test and Fisher's exact test for the categorical data. Logistic regression, Odds Ratio and 95%CI were used for definition of risk factors for mortality.
Results:
Of a total of 1,628 patients undergoing on-pump coronary artery bypass grafting, 141 (8.7%) died. The following risk factors for mortality were identified after logistic regression: dialysis (OR=7.61; 95%CI 3.58-16.20), neurologic dysfunction type I (OR=4.42; 95%CI 2.48-7.81), use of IABP (OR=3.38; 95%CI 1.98-5.79), cardiopulmonary bypass time (OR=3.09; 95%CI 2.04-4.68), serum creatinine on admission and peak values > 0.4mg/dL (OR=2.67; 95%CI 1.79-4.00), age > 65 years (OR=2.31; 95%CI 1.55-3.44), and time between hospital admission and and surgical procedure (OR=1.53; 95%CI 1.03-2.27).
Conclusion:
Dialysis, type I neurologic dysfunction, use of IABP, cardiopulmonary bypass time (> 115 minutes), serum creatinine on admission and peak values>0.4mg/dL, age > 65 years and time between hospital admission and surgical procedure were considered as risk factors for mortality in patients undergoing on-pump coronary artery bypass grafting surgery.
Related Concept Videos
01:23Peripheral Artery Disease V: Postoperative Nursing Management
01:30Coronary Artery Disease I: Introduction
01:28Cardiomyopathy VII: Pre and Post Operative Nursing Management
01:22Aneurysm IV: Nursing Management
01:26Coronary Artery Disease IV: Preventive Measures
01:27Coronary Artery Disease V: Interprofessional Care