Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

322
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
322
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

366
Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
366
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

876
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
876
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

384
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
384
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

279
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
279
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

209
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
209

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ethical Use of Cadaveric Images in Anatomical Textbooks, Atlases, and Journals: A Consensus Response From Authors and Editors.

Clinical anatomy (New York, N.Y.)·2025
Same author

Formation of the interatrial septum: Insights obtained from cardiac computed tomographic angiography.

Clinical anatomy (New York, N.Y.)·2024
Same author

Cardiac Outpouchings: Practical Approach to Normal Variants and Pathologic Conditions at CT and MRI.

Radiographics : a review publication of the Radiological Society of North America, Inc·2023
Same author

En Bloc AngioVac Removal of Thoracic Aortic Mass.

Texas Heart Institute journal·2021
Same author

Corrigendum to "Left Atrial Anatomy Relevant to Catheter Ablation".

Cardiology research and practice·2020
Same author

Left Atrial Appendage Mechanical Exclusion: Procedural Planning Using Cardiovascular Computed Tomographic Angiography.

Journal of thoracic imaging·2020
Same journal

The Banality of Cancer: Entropy As a Third Pillar of Lung Nodule Risk Assessment.

AJR. American journal of roentgenology·2026
Same journal

A Narrow Window for Artificial Intelligence-Generated Synthetic Temporal Bone CT From MRI.

AJR. American journal of roentgenology·2026
Same journal

From Uncertainty to Actionable Management: The Isolated Abnormal Axillary Lymph Node.

AJR. American journal of roentgenology·2026
Same journal

Beyond Detection: Translating Artificial Intelligence-Driven Opportunistic Screening Into Clinical Action.

AJR. American journal of roentgenology·2026
Same journal

Navigating PSMA PET Radiopharmaceuticals: Clinical and Operational Factors.

AJR. American journal of roentgenology·2026
Same journal

From Mesenteric Ischemia to Intestinal Stroke.

AJR. American journal of roentgenology·2026
See all related articles

Related Experiment Videos

Coronary plaque characterization using CT.

Farhood Saremi1, Stephan Achenbach

  • 11 Department of Radiology, University of Southern California, USC Keck Hospital, 1500 San Pablo St, Los Angeles, CA 90033.

AJR. American Journal of Roentgenology
|February 26, 2015
PubMed
Summary
This summary is machine-generated.

Coronary artery plaque composition varies, impacting rupture risk. Computed tomography (CT) shows potential for plaque characterization, despite current resolution limitations, aiding in identifying calcification, lipid-rich lesions, and positive remodeling.

Keywords:
cardiac CTcoronary CT angiography (CTA)coronary plaqueplaque characterization

Related Experiment Videos

Area of Science:

  • Cardiovascular Imaging
  • Pathology
  • Radiology

Background:

  • Coronary atherosclerotic plaque composition is heterogeneous.
  • Plaque composition influences the risk of plaque rupture and subsequent ischemic events.
  • Accurate histopathologic classification is crucial for understanding plaque behavior.

Purpose of the Study:

  • To review the histopathologic classification of coronary atherosclerotic plaques.
  • To evaluate the capabilities and limitations of computed tomography (CT) in assessing coronary artery plaques.

Main Methods:

  • Review of histopathologic classifications of coronary atherosclerotic plaques.
  • Analysis of current computed tomography (CT) technology for coronary plaque evaluation.
  • Discussion of CT's spatial, temporal, and contrast resolution limitations.

Main Results:

  • CT can identify plaque components, including calcification extent.
  • CT may differentiate lipid-rich from fibrous plaques.
  • CT can detect positive remodeling, an indicator of plaque vulnerability.

Conclusions:

  • Coronary plaque composition is variable and linked to rupture risk.
  • CT offers valuable, though limited, insights into coronary plaque characterization.
  • Despite resolution challenges, CT can provide clinically relevant information on plaque features.