Dendritic-cell-based technology landscape: Insights from patents and citation networks
Xiangjun Kong1, Yuanjia Hu, Zhifang Cai
1a State Key Laboratory of Quality Research in Chinese Medicine ; Institute of Chinese Medical Sciences; University of Macau ; Macau SAR , China.
Abstract:
As the most potent antigen-presenting cells, dendritic cells (DCs) are pivotal players in regulating immune responses. DC-based technologies have generated a series of typical and promising therapeutic options, especially after the first DC-based cancer vaccine was approved by US. Food and Drug Administration (US. FDA). In this context, this paper employs patents and citation networks to conduct a fundamental analysis in order to show overall landscape of DC-based technologies. The results in this research can be used as references for decision-making in developing efficacious DC therapeutic products.
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