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[Anaphylactic shock after i.v. verapamil].

H Rabinowitz, B Habot, A Fridensohn

    Harefuah
    |July 1, 1989
    PubMed
    Summary

    Verapamil, used for atrial fibrillation, can rarely cause anaphylactic shock. This patient recovered after treatment with corticosteroids and antihistamines, highlighting a rare but serious adverse effect.

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    Area of Science:

    • Cardiology
    • Pharmacology
    • Allergy and Immunology

    Background:

    • Verapamil is a commonly prescribed calcium channel blocker for supraventricular tachyarrhythmias like atrial fibrillation.
    • While generally safe, serious adverse effects of verapamil, though uncommon, necessitate vigilance.

    Observation:

    • A 61-year-old female patient on verapamil for atrial fibrillation experienced anaphylactic shock.
    • This presentation is a rare but critical adverse event associated with verapamil therapy.

    Findings:

    • The patient's anaphylactic shock was successfully managed with corticosteroids and antihistamines.
    • This case underscores the potential for severe hypersensitivity reactions to verapamil.

    Implications:

    • Clinicians should be aware of the rare risk of anaphylaxis with verapamil, even in patients with established indications.
    • Prompt recognition and management with appropriate medications are crucial for favorable outcomes in verapamil-induced anaphylaxis.

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