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Updated: Apr 16, 2026

Measurement of Heme Synthesis Levels in Mammalian Cells
Published on: July 9, 2015
[Insulin-like growth factor 1-induced changes in hemoporphyrin conformation in hemoglobin and NO-transporting
Abstract:
The evidence on the effect of different insulin-like growth factor concentrations on a state of human erythrocytes is provided. Activation of the insulin-like growth factor receptors led to changes in the conformation of hemoglobin, NO-transporting function in erythrocytes and also in micro-viscosity of the cell membrane. It was shown for the first time that at the binding of the insulin-like growth factor to a cell surface, hemoglobin of erythrocytes alters its conformations and affinity to ligands.
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