Related Experiment Video

Updated: Apr 16, 2026

Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis
06:38

Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis

Published on: October 12, 2016

10.6K

Management of segmental bone defects

Cyril Mauffrey, Brian Thomas Barlow, Wade Smith

    The Journal of the American Academy of Orthopaedic Surgeons
    |February 27, 2015
    PubMed

    Abstract:

    Segmental bone defects cause significant disability in patients. Modern orthopaedic surgical techniques have proved to be reliable for reconstruction of these defects. Autogenous bone graft remains the standard of care for reconstruction of small defects (<5 cm). Induced membrane technique and distraction osteogenesis are contemporary strategies of choice for reconstruction of larger bony defects. The use of vascularized fibular grafts has waned in popularity because of donor site morbidity and the success of alternative methods. Complications are ubiquitous with all methods of reconstruction for segmental bone defects but can be limited with careful surgical judgment and technique. In most cases, the rehabilitation period is prolonged, although some treatment options are shorter and enable a more active recovery than do others.

    More Related Videos

    A Reliable and Reproducible Critical-Sized Segmental Femoral Defect Model in Rats Stabilized with a Custom External Fixator
    08:20

    A Reliable and Reproducible Critical-Sized Segmental Femoral Defect Model in Rats Stabilized with a Custom External Fixator

    Published on: March 24, 2019

    9.5K
    Use of Human Perivascular Stem Cells for Bone Regeneration
    07:05

    Use of Human Perivascular Stem Cells for Bone Regeneration

    Published on: May 25, 2012

    22.4K

    Related Experiment Videos

    Last Updated: Apr 16, 2026

    Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis
    06:38

    Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis

    Published on: October 12, 2016

    10.6K
    A Reliable and Reproducible Critical-Sized Segmental Femoral Defect Model in Rats Stabilized with a Custom External Fixator
    08:20

    A Reliable and Reproducible Critical-Sized Segmental Femoral Defect Model in Rats Stabilized with a Custom External Fixator

    Published on: March 24, 2019

    9.5K
    Use of Human Perivascular Stem Cells for Bone Regeneration
    07:05

    Use of Human Perivascular Stem Cells for Bone Regeneration

    Published on: May 25, 2012

    22.4K

    Related Concept Videos

    Fractures: Bone Repair01:27

    Fractures: Bone Repair

    6.9K
    Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
    Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
    6.9K

    Articles linked to this work by shared authors, journal, and citation graph.

    Avoiding pitfalls in percutaneous acetabular column screw placement using combined fluoroscopic check-point views: a technical note and case series.

    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie·2026

    Learning curves in simulator-based training for percutaneous pelvic fixation: comparison between surgeons with and without prior fluoroscopy-guided percutaneous experience.

    Orthopaedics & traumatology, surgery & research : OTSR·2026

    Is the use of retrospectively collected radiographic scores an accurate method to determine time to union? A retrospective clinical cohort.

    Journal of orthopaedic trauma·2026

    The 100 most cited articles on acetabular fractures: an essential reading material.

    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie·2026

    Percutaneous screw fixation for traumatic Tile C pelvic fractures - Does the number of screws matter? A review of clinical and biomechanical outcomes.

    Injury·2026

    Endovascular thrombectomy for patients with large-core ischaemic stroke presenting up to 24 h after onset (ATLAS): a systematic review and individual patient data meta-analysis with central imaging adjudication.

    Lancet (London, England)·2026

    The Relationship Between Prone Range of Motion and Measured Femoral Version on Advanced Imaging in Adolescent Patients.

    The Journal of the American Academy of Orthopaedic Surgeons·2026

    Research in OsteoChondritis of the Knee-ROCK Research Study Group.

    The Journal of the American Academy of Orthopaedic Surgeons·2026

    Trends in Research Gap Years Among Orthopaedic Residency Applicants.

    The Journal of the American Academy of Orthopaedic Surgeons·2026

    Assessing Informed Consent in Orthopaedic Surgery Trainees: Does Quality or Comfort Level Vary by Training Year?

    The Journal of the American Academy of Orthopaedic Surgeons·2026

    Forecasting US Total Knee Arthroplasty Volumes to 2040: The Shift to Ambulatory Surgery Centers Has Just Begun.

    The Journal of the American Academy of Orthopaedic Surgeons·2026

    The Association of Long-Term Cardiac Issues for Adult Patients With Versus Without Scoliosis.

    The Journal of the American Academy of Orthopaedic Surgeons·2026

    Hyperelastic Cardiovascular NN-FE: A Framework for Integrating Nonlinear Finite Element Solvers with Neural Networks for the Hyperelastic Modeling of Cardiac Valve Tissue.

    Research square·2026

    Quantitative Gait Analysis in a Sheep Model of In-Utero Spina Bifida Repair.

    bioRxiv : the preprint server for biology·2026

    Ultrasound Tracking Reveals Progressive Regional Strain Differences in Human Achilles Tendons During Fatigue Loading.

    bioRxiv : the preprint server for biology·2026

    The construction and operation of type IV pili impose a variable energetic burden across phylogenetically distant bacteria.

    bioRxiv : the preprint server for biology·2026

    Detection of Osteoporotic Changes in Rat Femoral Bone Using the Acoustically Stimulated Electromagnetic (ASEM) Method.

    Ultrasound in medicine & biology·2026

    Mechanical evaluation of 3D-printed above-knee prosthetic sockets using a biofidelic hyperelastic silicone limb surrogate.

    Medical engineering & physics·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us