Related Experiment Video
Updated: Apr 16, 2026
08:43
Potentiodynamic Corrosion Testing
Published on: September 4, 2016
18.6K
Chromium content in the human hip joint tissues
Barbara Brodziak-Dopierała1, Jerzy Kwapuliński2, Krzysztof Sobczyk3
1School of Pharmacy with the Division of Laboratory Medicine, Department of Toxicology, Medical University of Silesia, 4 Jagiellonska, Str. 41-200 Sosnowiec, Poland.
Biomedical and Environmental Sciences : BES
|February 27, 2015
Summary
This study measured chromium levels in hip tissues, finding the highest concentration in cancellous bone and the lowest in the joint capsule. Chromium content differed significantly between osteoarthritis and fracture patients.
Area of Science:
- Biochemistry
- Orthopedics
- Trace Elements
Background:
- Chromium is essential for human health, but its role in bone tissue is not well understood.
- Understanding chromium distribution in hip tissues is crucial for osseous health research.
Purpose of the Study:
- To quantify chromium content in various hip joint tissues.
- To investigate potential differences in chromium levels related to hip joint conditions.
Main Methods:
- Analyzed 91 hip joint samples (66 female, 25 male) using Atomic Absorption Spectrometry (AAS).
- Tissues were anatomically separated, and chromium content was measured.
- Statistical analysis employed the U Mann-Whitney non-parametric test (P≤0.05).
Main Results:
- Highest chromium levels were found in cancellous bone (17.86 µg/g), followed by cancellous bone fragments (5.95 µg/g).
- Lowest chromium content was observed in the joint capsule (1.28 µg/g).
- Chromium levels were higher in patients with fractures (12.59 µg/g) compared to those with osteoarthritis (7.04 µg/g).
Conclusions:
- Cancellous bone exhibits the highest chromium concentration in hip joint tissues.
- Joint capsule has the lowest chromium concentration.
- Significant differences in chromium content exist between hip osteoarthritis and femoral neck fracture patients.
Related Concept Videos
02:36Chromatin Immunoprecipitation- ChIP
12.9K
Chromatin immunoprecipitation, or ChIP, is an antibody-based technique used to identify sites on DNA that bind to transcription factors of interest or histone proteins. It also helps determine the type of histone modifications such as acetylation, phosphorylation, or methylation.
Types of ChIP
ChIP can be divided into two types - X-ChIP and N-ChIP. X-ChIP involves in vivo cross-linking of histones and regulatory proteins to DNA, fragmenting the DNA by sonication, and isolating the protein-DNA...
Types of ChIP
ChIP can be divided into two types - X-ChIP and N-ChIP. X-ChIP involves in vivo cross-linking of histones and regulatory proteins to DNA, fragmenting the DNA by sonication, and isolating the protein-DNA...
12.9K
01:16Bones of the Lower Limb: Femur and Patella
9.8K
The femur is the body's longest and strongest bone spanning the thigh region. Its head articulates with the acetabulum of the hip bone to form the hip joint. A minor indentation on the medial side of the femoral head, called the fovea capitis, serves as the site of attachment for the ligament of the head of the femur. This weak ligament spans the femur and acetabulum and supports the hip joint. The narrowed region below the head is the neck of the femur. The inclination angle between the...
9.8K
01:19Bones of the Upper Limb: Humerus
14.6K
The upper limb consists of the arm, forearm, wrist, and hand bones. The humerus is the single bone of the upper arm region. Proximally, it has a large, spherical, smooth head that articulates with the glenoid cavity of the scapula to form the glenohumeral or shoulder joint. The margin of the head is the anatomical neck, a residual epiphyseal plate. Laterally it extends to form bony projections called the greater tubercle and the lesser tubercle. Next to the tubercles is the surgical neck, a...
14.6K