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Updated: Apr 16, 2026

Site-Specific Lysine Lactylation via Genetic Code Expansion in E. coli and Mammalian Cells
Published on: February 24, 2026
Type-B lactic acidosis associated with progressive multiple myeloma
Sameer Y Abdullah1, Moaath K Ali, Marwa M Sabha
1Department of Internal Medicine, Medical Oncology Division, King Hussein Cancer Center, Al-Jubeiha, Amman 11941, Jordan. Fax. +962 (6) 5353001. E-mail. syaser@khcc.jo.
Abstract:
We report a 64-year-old lady with stage II, Immunoglobulin-G lambda multiple myeloma (MM) (standard risk), who presented with type-B lactic acidosis (LA), and multi-organ dysfunction associating myeloma progression, and ending in imminent death. In the context of literature review of all previously reported similar cases, this report highlights and discusses the association of type-B LA and MM (especially progressive disease), and also emphasizes the poor outcome. Early recognition of this condition with intensive supportive care, and treatment of multiple myeloma may improve outcomes.
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