Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Oogenesis02:07

Oogenesis

71.7K
In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
71.7K
Oogenesis01:22

Oogenesis

5.3K
Oogenesis,  the process of developing egg cells (female gametes), occurs within the ovaries and is fundamental to female fertility. This sequence begins during fetal development when diploid oogonia in the developing ovaries undergo mitotic divisions to produce primary oocytes. By birth, these primary oocytes enter prophase I of meiosis but become arrested in this stage, remaining suspended until puberty.
Each primary oocyte is surrounded by a layer of pre-granulosa cells, forming what is...
5.3K
Mitochondria01:37

Mitochondria

21.6K
Mitochondria are eukaryotic cellular organelles that are known to produce energy through a process called oxidative phosphorylation. Besides their primary function, mitochondria are involved in various cellular processes, including cell growth, differentiation, signaling, metabolism, and senescence. Age-related changes cause a decline in mitochondrial quality and integrity due to increased mitochondrial mutations and oxidative damage. Thus, aging can severely impact mitochondrial functions,...
21.6K
Meiosis vs. Mitosis02:57

Meiosis vs. Mitosis

75.4K
Cell division is necessary for growth and reproduction in organisms. Mitosis aids cell growth and development by dividing somatic cells. In contrast, meiosis causes the division of germ cells and plays an essential role in sexual reproduction. Due to their unique functional requirements, mitosis and meiosis differ from each other in multiple aspects.
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
75.4K
Animal Mitochondrial Genetics02:59

Animal Mitochondrial Genetics

10.2K
Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...
10.2K
Mitochondrial Membranes01:45

Mitochondrial Membranes

18.0K
A single mitochondrion is a bean-shaped organelle enclosed by a double-membrane system. The outer membrane of mitochondria is smooth and contains many porins - the integral membrane transporters. Porins enable free diffusion of ions and small uncharged molecules through the outer mitochondrial membrane but limit the transport of molecules larger than 5000 Daltons. Further, the outer mitochondrial membrane forms a unique structure called membrane contact sites with other subcellular organelles,...
18.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cumulus Expansion and Oocyte Quality Across the Pubertal Transition in Mice: Implications for Modeling Fertility Preservation in Adolescents.

Research square·2026
Same author

Obesity is associated with an increased risk of early pregnancy loss after euploid frozen embryo transfer.

Fertility and sterility·2026
Same author

Bilateral ovarian abscesses following platelet-rich plasma injection for "ovarian rejuvenation": a case report.

F&S reports·2026
Same author

Impact of residential air pollution on in vitro fertilization (IVF) outcomes in New Jersey.

Journal of assisted reproduction and genetics·2026
Same author

The effect of changing endometrial preparation protocols on pregnancy outcomes after initial, unsuccessful euploid frozen embryo transfer.

Reproductive biomedicine online·2026
Same author

Impact of pregnancy loss following assisted reproductive treatment on outcomes of subsequent cycles.

Current opinion in obstetrics & gynecology·2026
Same journal

Management of hypertensive disorders in pregnancy.

Current opinion in obstetrics & gynecology·2026
Same journal

Updates in group prenatal care research.

Current opinion in obstetrics & gynecology·2026
Same journal

Complex benign gynecology in perimenopause: current evidence and future directions.

Current opinion in obstetrics & gynecology·2026
Same journal

Role of insulin in female reproduction.

Current opinion in obstetrics & gynecology·2026
Same journal

Urinary tract involvement in endometriosis: current evidence and clinical insights into navigating diagnosis and management.

Current opinion in obstetrics & gynecology·2026
Same journal

Updates in ultrasound imaging of adenomyosis and clinical impacts.

Current opinion in obstetrics & gynecology·2026
See all related articles

Related Experiment Video

Updated: Apr 16, 2026

Studying Mitochondrial Structure and Function in Drosophila Ovaries
09:53

Studying Mitochondrial Structure and Function in Drosophila Ovaries

Published on: January 4, 2017

25.0K

Oocyte mitochondrial function and reproduction.

Elnur Babayev1, Emre Seli

  • 1Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, Connecticut, USA.

Current Opinion in Obstetrics & Gynecology
|February 27, 2015
PubMed
Summary
This summary is machine-generated.

Mitochondria are vital for fertility, impacting egg development and embryo growth. Addressing mitochondrial dysfunction through nutrients or replacement therapies shows promise for reproductive health and preventing genetic diseases.

More Related Videos

In Situ Labeling of Mitochondrial DNA Replication in Drosophila Adult Ovaries by EdU Staining
10:31

In Situ Labeling of Mitochondrial DNA Replication in Drosophila Adult Ovaries by EdU Staining

Published on: October 15, 2016

9.7K
Use of Bisection to Reduce Mitochondrial DNA in the Bovine Oocyte
06:15

Use of Bisection to Reduce Mitochondrial DNA in the Bovine Oocyte

Published on: July 6, 2022

2.7K

Related Experiment Videos

Last Updated: Apr 16, 2026

Studying Mitochondrial Structure and Function in Drosophila Ovaries
09:53

Studying Mitochondrial Structure and Function in Drosophila Ovaries

Published on: January 4, 2017

25.0K
In Situ Labeling of Mitochondrial DNA Replication in Drosophila Adult Ovaries by EdU Staining
10:31

In Situ Labeling of Mitochondrial DNA Replication in Drosophila Adult Ovaries by EdU Staining

Published on: October 15, 2016

9.7K
Use of Bisection to Reduce Mitochondrial DNA in the Bovine Oocyte
06:15

Use of Bisection to Reduce Mitochondrial DNA in the Bovine Oocyte

Published on: July 6, 2022

2.7K

Area of Science:

  • Reproductive Biology
  • Cellular Biology
  • Mitochondrial Medicine

Background:

  • Mitochondria are crucial for cellular energy production.
  • Emerging evidence highlights their significant role in oocyte development and overall reproductive function.
  • Mitochondrial dysfunction is increasingly linked to decreased fertility and reproductive challenges.

Purpose of the Study:

  • To review recent animal and clinical studies on the role of mitochondria in fertility.
  • To analyze the impact of assisted reproductive techniques (ARTs) on mitochondrial function.
  • To discuss future clinical applications of mitochondrial nutrients and mitochondrial replacement.

Main Methods:

  • Review of current animal and clinical research.
  • Analysis of data on assisted reproductive techniques (ARTs) and mitochondrial function.
  • Exploration of emerging therapeutic strategies including mitochondrial nutrients and replacement.

Main Results:

  • Mitochondria are essential for oocyte maturation, fertilization, and embryonic development.
  • Mitochondrial dysfunction negatively impacts oocyte quality and embryonic development.
  • Assisted reproductive techniques (ARTs) can affect mitochondrial function, while nutrients may enhance it.

Conclusions:

  • Mitochondrial health is critical for successful reproduction; abnormalities have severe consequences.
  • Boosting mitochondrial activity with specific compounds may offer clinical benefits for fertility.
  • Mitochondrial replacement therapies present a potential strategy for preventing mitochondrial diseases.