Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

14.8K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
14.8K
Arteries of the Head and Neck01:26

Arteries of the Head and Neck

4.7K
The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
4.7K
Veins of Head and Neck01:19

Veins of Head and Neck

7.4K
The blood drainage from the head and neck is primarily managed by three pairs of veins: the external jugular, internal jugular, and vertebral veins. The external jugular veins drain superficial scalp and face structures, passing over the sternocleidomastoid muscles to empty into the subclavian veins.
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
7.4K
Muscles that Move the Head01:19

Muscles that Move the Head

7.6K
The muscles that move the head are a dynamic and complex group of structures that work together to facilitate a wide range of head movements, including rotation, flexion, extension, and lateral bending.
The bilateral sternocleidomastoid, or SCM, and the suprahyoid and infrahyoid muscles are significant head flexors. The SCM muscles originate at the sternum and clavicle and attach to the mastoid process of the temporal bone. The SCM contracts bilaterally to bend the head forward, whereas...
7.6K
Vascular Spasm01:16

Vascular Spasm

5.1K
The vascular phase, also known as vasospasm, is the initial stage of hemostasis, crucial for preventing excessive bleeding when a blood vessel is injured. After a vessel is cut, nerves in the damaged area trigger pain and other sensory impulses. Simultaneously, the smooth muscles in the vessel wall contract, resulting in a vascular spasm. This contraction reduces the vessel's diameter at the injury site, slowing or stopping blood loss through the vessel wall. Vascular spasms typically last...
5.1K
Glaucoma: Overview01:25

Glaucoma: Overview

1.7K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Temporary occipital nerve stimulation as transitional therapy for chronic intractable cluster headache: A case report and proof of concept.

Headache·2026
Same author

There's more fun than work: Neurologist Walter Shelden's atypical work-life balance in early 20th century medicine.

Proceedings (Baylor University. Medical Center)·2025
Same author

Curriculum Innovations: A Novel Neurology Clinician-Educator Program.

Neurology. Education·2025
Same author

Leonard Rowntree, Louis Wilson, Fielding Garrison, and the origins of teaching medical history at the Mayo Clinic.

Proceedings (Baylor University. Medical Center)·2024
Same author

The Auxiliary to the American Academy of Neurology.

Neurology·2024
Same author

History of migraine.

Handbook of clinical neurology·2023
Same journal

Practice Patterns and Care Gaps in Lennox Gastaut Syndrome: A call for Action.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques·2026
Same journal

Isolated Achiasma Discovered at Age 86: A Rare Cause of see-saw nystagmus and bitemporal hemianopia.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques·2026
Same journal

Post-Stroke Parakinesia Brachialis Oscitans: Clinical Insights from a Case Series.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques·2026
Same journal

A Neuronal Perspective.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques·2026
Same journal

Diagnostic efficacy, costs, and safety of portable ultra-low field MRI in brain imaging: a systematic review.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques·2026
Same journal

Chronology of Non-Motor Symptoms in 100 Patients with Advanced PD of 10 Years' Duration: Pre- versus Post-Motor Period.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques·2026
See all related articles

Related Experiment Video

Updated: Apr 16, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

18.9K

Osler on migraine.

Christopher J Boes1

  • 1Mayo Clinic,Department of Neurology,Rochester,MN,USA.

The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
|February 28, 2015
PubMed
Summary
This summary is machine-generated.

William Osler, despite being called a therapeutic nihilist, detailed numerous migraine treatments in his influential 1892 textbook. His recommendations, including cannabis, were comprehensive for his era.

Keywords:
William Osler

More Related Videos

Author Spotlight: Minimally Invasive Relief for Occipital Neuralgia at the Nuchal Line
04:06

Author Spotlight: Minimally Invasive Relief for Occipital Neuralgia at the Nuchal Line

Published on: September 13, 2024

4.1K
Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache
05:40

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Published on: July 29, 2021

10.3K

Related Experiment Videos

Last Updated: Apr 16, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

18.9K
Author Spotlight: Minimally Invasive Relief for Occipital Neuralgia at the Nuchal Line
04:06

Author Spotlight: Minimally Invasive Relief for Occipital Neuralgia at the Nuchal Line

Published on: September 13, 2024

4.1K
Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache
05:40

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Published on: July 29, 2021

10.3K

Area of Science:

  • Medical History
  • Neurology

Background:

  • William Osler's 1892 textbook, 'The Principles and Practice of Medicine,' was a highly influential medical publication.
  • Osler was sometimes perceived as a therapeutic nihilist, a view this study examines regarding his approach to migraine treatment.

Discussion:

  • This study reviews Osler's specific therapeutic recommendations for migraine management as presented in his textbook.
  • Preventive treatments mentioned by Osler included bromides, iron, arsenic, nitroglycerin, and cannabis.
  • Acute migraine treatments suggested by Osler encompassed coffee, chloroform, cannabis, antipyrin, antifebrin, phenacetin, caffeine citrate, nux vomica, and ergot.

Key Insights:

  • Osler's treatment recommendations for migraine were not indicative of therapeutic nihilism and aligned with contemporary medical practices.
  • Cannabis was considered by Osler to be the most effective remedy for acute migraine attacks.
  • Osler's textbook did not introduce novel personal experiences but synthesized existing knowledge on migraine.

Outlook:

  • Osler's clear and concise summary of migraine treatment significantly influenced practicing physicians due to the textbook's widespread adoption.
  • This historical review provides context for understanding the evolution of migraine therapeutics and the impact of seminal medical texts.