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Updated: Apr 16, 2026

Flow Cytometric Analysis of Biomarkers for Detecting Human Sperm Functional Defects
Published on: April 21, 2022
Number of sons contributes to ageing-associated inflammation
Saara Marttila1, Tapio Nevalainen1, Laura Kananen1
11] Department of Microbiology and Immunology, School of Medicine, University of Tampere, Tampere, Finland [2] Gerontology Research Center, Tampere, Finland.
Abstract:
The rate of inflammation increases in elderly individuals, a phenomenon called inflammaging, and is associated with degenerative diseases. However, the causes of inflammaging and the origin of the associated inflammatory mediators have remained enigmatic. We show herein that there is a positive correlation between the number of sons born and C-reactive protein concentrations in 90-year-old women. This association is influenced by HLA genetics known to regulate the immune response against HY antigens.
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