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Genetic factors affecting dental caries risk.
1Department of Pediatric and Preventive Dentistry, BRS Dental College, Panchkula, Haryana, India.
Australian Dental Journal
|February 28, 2015
Summary
Genetic factors play a role in dental caries, alongside environmental influences. Identifying genetic risks can improve prevention and treatment strategies for this complex disease.
Area of Science:
- Oral Health
- Genetics
- Dental Public Health
Background:
- Dental caries is a complex disease influenced by multiple factors.
- Understanding the genetic basis of dental caries is crucial for developing targeted interventions.
- The disease model of caries is rapidly evolving, particularly in the post-genomic era.
Purpose of the Study:
- To review the existing literature on the genetic aspects of dental caries.
- To provide a framework for understanding the genetic contributions to caries aetiology.
- To explore the implications of genetic research for future oral healthcare.
Main Methods:
- Systematic literature search of the PubMed database using keywords: 'caries', 'genetics', 'taste', 'diet', 'twins'.
- Extensive handsearching of reference lists from relevant articles.
- Review and synthesis of findings on genetic factors influencing dental caries.
Main Results:
- Evidence supports a significant role for genetic factors in the aetiology of dental caries.
- Both genetic and environmental factors are implicated in the development of caries.
- Taste genetics and dietary habits are among the factors influenced by genetics.
Conclusions:
- Genes contribute to an individual's susceptibility to dental caries.
- Further research is needed to replicate findings in diverse populations.
- Identifying genetic risk factors can enhance personalized prevention and treatment strategies for dental caries.
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