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Somatostatin treatment of gastrointestinal fistulae
C Palnaes Hansen1, J Hegnhøj, O Olsen
1Department of Medical Gastroenterology P, Rigshospitalet, University of Copenhagen, Denmark.
Abstract:
Output from gastrointestinal fistulae to the skin was measured in five patients during total parenteral nutrition and restricted oral intake. Supplemental infusion of somatostatin during six days caused a significant reduction in discharge in all patients compared to the pretreatment level, but none of the fistulae closed as a result of the treatment. Somatostatin may be considered an adjuvant drug to parenteral nutrition and restricted oral intake in the conservative treatment of external fistulae from the gastrointestinal tract.