[Urinary incontinence induced by the antidepressants - case report]

Area of Science:

• Pharmacology
• Urology

Background:

• Antidepressants can influence central nervous system neurotransmitters affecting lower urinary tract function.
• Mirtazapine is a commonly prescribed antidepressant with potential anticholinergic and alpha-adrenergic blocking effects.

Observation:

• A 55-year-old patient presented with urinary incontinence, initially considered for surgical intervention.
• Detailed history revealed mirtazapine use as a potential causative agent for the incontinence.

Findings:

• Discontinuation of mirtazapine led to complete resolution of urinary incontinence.
• This case demonstrates mirtazapine-induced urinary incontinence, a less common side effect.

Implications:

• Clinicians should consider antidepressant-induced urinary incontinence in differential diagnoses.
• Identifying drug-induced incontinence can prevent unnecessary surgical procedures and restore continence effectively.