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Fourier transform acousto-optic imaging with a custom-designed CMOS smart-pixels array.

Kinia Barjean, Kevin Contreras, Jean-Baptiste Laudereau

|February 28, 2015

Summary

Acousto-optic imaging (AOI) now offers axial resolution using Fourier Transform analysis. This technique shows potential for real-time imaging in biological tissues with good signal-to-noise ratio.

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Area of Science:

Optics and Photonics
Biomedical Imaging
Signal Processing

Background:

Scattering media, like biological tissues, impede deep imaging.
Acousto-optic imaging (AOI) offers a way to image through scattering media.
Achieving axial resolution in AOI has been a significant challenge.

Purpose of the Study:

To introduce and demonstrate Fourier Transform acousto-optic imaging (FT-AOI) for enhanced resolution.
To evaluate the performance of FT-AOI in terms of signal-to-noise ratio and acquisition speed.
To assess the feasibility of FT-AOI for in vivo applications.

Main Methods:

Implementation of an AOI system utilizing Fourier Transform (FT) analysis.
Employment of a CMOS smart-pixels sensor for real-time speckle pattern analysis.
Development of a measurement system for high-speed data acquisition.

Main Results:

Successful demonstration of axial resolution in acousto-optic imaging.
Achieved signal-to-noise ratio comparable to AOI methods without axial resolution.
Demonstrated acquisition rates suitable for imaging dynamic biological samples.

Conclusions:

FT-AOI is a viable technique for achieving axial resolution in scattering media.
The developed system offers a promising balance of resolution, signal quality, and speed.
FT-AOI holds potential for future biomedical imaging applications in living tissues.