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Updated: Apr 16, 2026

A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
Disseminated emm Type 12 Group A Streptococcus and Review of Invasive Disease
Arielle L Heeke1, Henry M Blumberg, Jason M Perry
1Department of Medicine (ALH, JMP), Emory University School of Medicine, Atlanta, Georgia; Division of Infectious Diseases (HMB, DSW, EKS, SWS, JLS), Department of Medicine, Emory University School of Medicine, Atlanta, Georgia; and Atlanta Veterans Administration Medical Center (SWS), Decatur, Georgia.
Abstract:
The authors present a case of invasive group A Streptococcus (GAS) in a previously healthy 63-year-old male complicated by trans-esophageal echocardiogram negative endocarditis, septic arthritis, and multiple cerebral septic emboli. Despite antibiotics and drainage of his largest brain abscess, the patient expired. This case highlights the potential mortality from invasive GAS disease. Included is a review of current literature regarding invasive GAS that addresses its presentation, prevalence, virulence and treatment.
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