KLF1-null neonates display hydrops fetalis and a deranged erythroid transcriptome

Graham W Magor1, Michael R Tallack2, Kevin R Gillinder1

  • 1Mater Research Institute, Faculty of Medicine and Biomedical Sciences, The University of Queensland, Woolloongabba, QLD, Australia;

Blood
|March 1, 2015
PubMed
Summary

Severe neonatal anemia and jaundice in a KLF1-null infant highlight the critical role of KLF1 in red blood cell development and hemoglobin switching.