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Need for chronic kidney disease prevention programs in disadvantaged populations
Norberto Perico1, Giuseppe Remuzzi
1Clinical Research Center for Rare Diseases "Aldo e Cele Dacco" - IRCCS Istituto di Ricerche Farmacologiche Mario Negri, and Department of Medicine, Unit of Nephrology and Dialysis, A.O. Papa Giovanni XXIII, Bergamo, Italy.
Chronic kidney disease (CKD) poses a global health threat. Early recognition and management of CKD, especially in resource-poor areas, can slow progression and improve patient outcomes.
Area of Science:
- Nephrology
- Public Health
- Non-communicable Diseases
Background:
- Chronic kidney disease (CKD) significantly worsens outcomes for major non-communicable diseases, representing a leading global cause of death.
- The full extent of CKD as a worldwide public health issue is often underestimated.
- Early identification of CKD and co-morbidities can potentially slow disease progression, enhance longevity, improve quality of life, and reduce healthcare expenditures.
Purpose of the Study:
- To highlight the global public health significance of chronic kidney disease (CKD).
- To discuss the challenges and potential strategies for CKD screening and management, particularly in resource-poor settings.
- To emphasize the importance of multimodal tools in preventing CKD and its complications.
Main Methods:
- Review of existing literature and public health data concerning CKD prevalence and impact.
- Analysis of the effectiveness of early recognition and management strategies for CKD.
- Evaluation of multimodal approaches for CKD prevention and treatment adaptation for diverse socioeconomic contexts.
Main Results:
- Effective strategies exist to prevent CKD by managing risk factors and slow progression to end-stage renal disease (ESRD).
- Implementation of management strategies has shown a reduction in the incidence of ESRD.
- Adapted approaches can be effective even in the poorest populations at high risk for CKD.
Conclusions:
- Addressing renal health, particularly in disadvantaged populations, is crucial for global health equity.
- Preventing ESRD through timely CKD management can reduce the burden of unaffordable renal replacement therapies.
- Multimodal interventions offer a promising pathway to mitigate the impact of CKD worldwide.
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Chronic Kidney Disease I: Introduction
Chronic Kidney Disease III: Interprofessional Care
Acute Kidney Injury IV: Diagnostic Studies and Prevention
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Chronic Kidney Disease II: Clinical Manifestations
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