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The Kidney Early Evaluation Program (KEEP) of Japan.

Kosaku Nitta1, Kazuyoshi Okada, Mitsuru Yanai

  • 1International Kidney Evaluation Association Japan (IKEAJ), Tokyo, Japan.

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|March 1, 2015
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Summary

This study identified key risk factors for chronic kidney disease (CKD) in Japan. Controlling hypertension, diabetes, and high blood pressure is crucial for preventing CKD onset and progression.

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Area of Science:

  • Nephrology
  • Public Health
  • Epidemiology

Background:

  • Chronic kidney disease (CKD) poses a significant public health challenge.
  • Early detection and risk factor identification are crucial for managing CKD.
  • The International Kidney Evaluation Association Japan (IKEAJ) initiative screens high-risk populations.

Purpose of the Study:

  • To retrospectively analyze data from the KEEP Japan cohort.
  • To identify risk factors associated with the onset and progression of CKD.
  • To inform public health strategies for CKD prevention.

Main Methods:

  • Retrospective analysis of data from 1,947 participants enrolled in KEEP Japan.
  • Statistical examination to determine odds ratios for CKD occurrence.
  • Inclusion criteria focused on participants screened by IKEAJ.

Main Results:

  • Over 70% of participants did not have CKD; 7.5% were classified as high risk.
  • Hypertension history and age over 60 were significant risk factors for CKD occurrence.
  • Diabetes, cardiovascular disease, high blood pressure, anemia, and low HDL-C were associated with increased CKD risk.

Conclusions:

  • Appropriate management of blood pressure, blood glucose, anemia, and HDL-C is vital.
  • Targeted interventions for individuals with identified CKD risk factors can reduce disease incidence.
  • Public health awareness and screening programs like IKEAJ are essential for CKD prevention.