Pregnancy outcome following myomectomy

Area of Science:

• Reproductive Medicine
• Gynecologic Surgery
• Obstetrics

Background:

• Uterine fibroids are common, often requiring treatment that balances symptom relief with fertility preservation.
• Abdominal myomectomy remains a crucial surgical option for women desiring future pregnancies in resource-limited settings.

Purpose of the Study:

• To evaluate pregnancy outcomes following abdominal myomectomy in women with symptomatic uterine fibroids who wished to retain their fertility.
• To assess the safety and efficacy of microsurgical myomectomy in improving conception rates and live birth outcomes.

Main Methods:

• A prospective observational study was conducted with 40 women undergoing microsurgical abdominal myomectomy.
• Participants were followed for up to 24 months, with data collected via questionnaires and telephone/outdoor visits.
• Post-operative hysterosalpingography was performed, and conception attempts were advised after 16 weeks.

Main Results:

• Of 40 women, 14 (35%) conceived, with a median time of 1-2 years post-surgery.
• Spontaneous conception occurred in 71.4% of cases.
• 12 out of 14 (85.7%) conceived women delivered live babies via Cesarean section, with most newborns weighing over 3kg.

Conclusions:

• Abdominal myomectomy is an effective fertility-preserving surgical procedure for women with uterine fibroids.
• The study demonstrates a significant conception and live birth rate following myomectomy, supporting its role in managing subfertility related to fibroids.