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Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
Published on: April 12, 2021
[Longitudinal study of the metabolic syndrome after kidney transplantation]
Rafael Fernández Castillo1, Ruth Fernández Gallegos2, Gloria María Zaragoza Fernández3
1Universidad de Granada. Facultad de Ciencias de la Salud. Departamento de Enfermería.. rafaelfernandez@ugr.es.
Background:
The occurence of the metabolic syndrome (MS) between the renal receptors is one of the major complications after transplantation and is associated with an increased risk of graft failure and high rates of obesity and diabetes new appearance.
Aims:
This study aims to investigate the prevalence and risk factors associated with the development of the MS and to evaluate the association between the same with the allograft dysfunction.
Methods:
The samples consisted of 138 renal transplant patients, 83 men and 55 women, kidney transplant, which was attended by over five years for the transplant consultation. Were analyzed as potential risk factors for MS: age, sex, body mass index (BMI), weight, hypertension, diabetes, LDL, HDL, triglycerides in serum and immunosuppressive therapy (cyclosporine, tacrolimus, mycophenolate mofetil), was also assessed the prevalence of acute rejection episodes and renal function.
Results:
The prevalence of MS was 39.85 %. As statistically significant risk factors were obtained the BMI, overweight, HDL cholesterol levels, triglycerides and LDL as well as hypertension and diabetes. There were high rates of acute rejection and differences in story to the glomerular filtration rate.
Conclusions:
There is a high prevalence of the MS that severely compromised renal function and graft survival in renal transplant patients, it is very important the control and strict monitoring of all risk factors identified.
Insights
Metabolic syndrome (MS) affects nearly 40% of kidney transplant patients, increasing graft failure risk. Strict monitoring of factors like BMI, hypertension, and diabetes is crucial for better outcomes.
Area of Science:
- Nephrology
- Transplantation Immunology
- Metabolic Disorders
Background:
- Metabolic syndrome (MS) is a significant post-transplant complication.
- MS is linked to increased graft failure, obesity, and new-onset diabetes.
- Understanding MS prevalence and risk factors in renal transplant recipients is critical.
Purpose of the Study:
- To determine the prevalence of MS in renal transplant patients.
- To identify risk factors associated with MS development.
- To evaluate the association between MS and allograft dysfunction.
Main Methods:
- Study included 138 renal transplant patients (83 male, 55 female) followed for over five years.
- Analyzed risk factors: BMI, weight, hypertension, diabetes, lipids (LDL, HDL, triglycerides), and immunosuppressants.
- Assessed acute rejection episodes and renal function (glomerular filtration rate).
Main Results:
- The prevalence of MS was 39.85%.
- Significant risk factors included BMI, overweight, HDL, triglycerides, LDL, hypertension, and diabetes.
- High rates of acute rejection and impaired glomerular filtration rate were observed.
Conclusions:
- High MS prevalence significantly compromises renal function and graft survival.
- Strict control and monitoring of identified risk factors are essential.
- Early intervention can mitigate MS impact on transplant outcomes.
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Related Concept Videos
01:28Kidney Transplant I: Introduction
01:26Kidney Transplant II: Surgical Procedure
01:16Kidney Transplant III: Nursing Management
01:25Chronic Kidney Disease I: Introduction
01:24Chronic Kidney Disease II: Clinical Manifestations
01:30Acute Kidney Injury IV: Diagnostic Studies and Prevention